Research Article

Degos' disease: association with anticardiolipin antibodies and the lupus anticoagulant.

Br Med J (Clin Res Ed) 1984; 289 doi: https://doi.org/10.1136/bmj.289.6445.576 (Published 08 September 1984) Cite this as: Br Med J (Clin Res Ed) 1984;289:576
  1. H J Englert,
  2. C H Hawkes,
  3. M L Boey,
  4. G J Derue,
  5. S Loizou,
  6. E N Harris,
  7. A E Gharavi,
  8. R G Hull,
  9. G R Hughes

    Abstract

    A woman presented with multiple cerebral thromboses and skin lesions characteristic of Degos' disease. Her serum contained high titres of anticardiolipin antibodies and showed lupus anticoagulant activity, both known to be strong markers of a thrombotic tendency in systemic lupus erythematosus. This finding may have therapeutic implications for this usually fatal disease.