Research Article

Urethral syndrome: a self limiting illness.

Br Med J (Clin Res Ed) 1984; 288 doi: (Published 05 May 1984) Cite this as: Br Med J (Clin Res Ed) 1984;288:1349
  1. T C O'Dowd,
  2. C D Ribeiro,
  3. J Munro,
  4. R R West,
  5. C H Howells,
  6. R H Davis


    Thirty nine adult women who were not pregnant and had the urethral syndrome in a general practice underwent detailed microbiological investigations. Patients monitored their own symptoms, and those with persisting symptoms were entered into a randomised controlled trial of treatment with doxycycline and placebo. Chlamydia trachomatis and Neisseria gonorrhoeae were not isolated and fastidious organisms were not causally associated with the urethral syndrome. Treatment with doxycycline showed no benefit; each episode of the urethral syndrome was short and self limiting and there were no recurrences in a median observation period of 12 months.