Research Article

Gonadal function in men treated for acute leukaemia.

Br Med J (Clin Res Ed) 1983; 287 doi: https://doi.org/10.1136/bmj.287.6399.1093 (Published 15 October 1983) Cite this as: Br Med J (Clin Res Ed) 1983;287:1093
  1. J Waxman,
  2. Y Terry,
  3. L H Rees,
  4. T A Lister

    Abstract

    Gonadal function was assessed in eight men in remission of leukaemia who had completed treatment eight months to eight years previously. All four men treated for acute myeloid leukaemia had normal sperm counts and motility, compared with only one of the four with acute lymphatic or undifferentiated leukaemia. Hormonal studies indicated that the sterility resulted from gonadal failure rather than pituitary dysfunction after cranial irradiation. These findings are important in the counselling of patients with leukaemia.