Research Article

Urinary red-cell morphology during exercise.

Br Med J (Clin Res Ed) 1982; 285 doi: https://doi.org/10.1136/bmj.285.6353.1455 (Published 20 November 1982) Cite this as: Br Med J (Clin Res Ed) 1982;285:1455
  1. R G Fassett,
  2. J E Owen,
  3. J Fairley,
  4. D F Birch,
  5. K F Fairley

    Abstract

    Midstream urine samples were examined by phase-contrast microscopy before and immediately after 48 subjects participated in a long-distance run. Minor abnormalities were found in six samples before exercise. Eighteen subjects developed proteinuria and five haematuria on dipstick testing after exercise. Forty-four subjects had increased urinary red-cell counts after exercise; of these, 33 had counts above the normal range (800/ml). In all subjects urinary red cells were dysmorphic both before and after exercise, indicating a glomerular source. Ten subjects developed red-cell casts and 42 showed an increase in hyaline and hyaline-granular casts after exercise. There were modest increases in urinary white-cell counts in 35 subjects but little change in urine pH or osmolality with exercise. This study confirms that urinary red-cell counts commonly increase appreciably after exercise. The dysmorphic appearance of the red cells together with the presence of red-cell casts indicates a glomerular source for this common form of exercise haematuria.