Research Article

Further field testing of the more heat-stable measles vaccines in Cameroon.

Br Med J (Clin Res Ed) 1982; 285 doi: https://doi.org/10.1136/bmj.285.6341.531 (Published 21 August 1982) Cite this as: Br Med J (Clin Res Ed) 1982;285:531
  1. D L Heymann,
  2. E L Smith,
  3. J H Nakano,
  4. J G Jato,
  5. G E Martin,
  6. G K Maben

    Abstract

    Two of the more heat-stable measles vaccines were field tested in Cameroon. Both maintained the minimum required infectivity titre and the ability to induce seroconversion after storage unreconstituted at 37 degrees C for 14 days. One of the vaccines, studied after reconstitution, maintained its ability to induce seroconversion after reconstitution and storage at 25 degrees C for 48 hours and at 37 degrees C for at least four hours. The increased heat stability of the studied vaccines will not eliminate the need for a well-monitored system of vaccine conservation and distribution but will ease the rigid cold-storage requirements of conventional measles vaccines.