Research Article

Assessment of iron stores in inflammation by assay of serum ferritin concentrations.

Br Med J (Clin Res Ed) 1981; 283 doi: https://doi.org/10.1136/bmj.283.6300.1147 (Published 31 October 1981) Cite this as: Br Med J (Clin Res Ed) 1981;283:1147
  1. D R Blake,
  2. R F Waterworth,
  3. P A Bacon

    Abstract

    A serum ferritin concentration of below 15 microgram/l is accepted as indicating diminished iron reserves in an otherwise normal person. In patients with inflammatory disease this lower limit of normality may be inappropriate as inflammation may directly stimulate the production of ferritin protein. Results obtained in a survey of 150 patients with early inflammatory joint disease suggest that a ferritin concentration of 55 microgram/l is a more appropriate lower limit of normality.