Research Article

Improved survival after orthotopic liver grafting.

Br Med J (Clin Res Ed) 1981; 283 doi: (Published 11 July 1981) Cite this as: Br Med J (Clin Res Ed) 1981;283:115
  1. R Y Calne,
  2. R Williams,
  3. M Lindop,
  4. J V Farman,
  5. M E Tolley,
  6. K Rolles,
  7. B MacDougall,
  8. J Neuberger,
  9. R J Wyke,
  10. A T Raftery,
  11. T J Duffy,
  12. D G Wight,
  13. D J White


    A total of 108 orthotopic liver transplants have been carried out in the Cambridge/King's College Hospital series. Over 13 years, changes in patient selection, immunosuppression, and surgical and anaesthetic techniques have led to a steady improvement in results. Results obtained in the last 22 patients indicated that over half survive for one year. Although at considerable risk during the operation, patients with non-malignant cirrhotic diseases who survive one year have a good long-term chance of survival