Research Article

Haemolytic anaemia after cisplatin treatment.

Br Med J (Clin Res Ed) 1981; 282 doi: https://doi.org/10.1136/bmj.282.6281.2003 (Published 20 June 1981) Cite this as: Br Med J (Clin Res Ed) 1981;282:2003
  1. J A Levi,
  2. R S Aroney,
  3. D N Dalley

    Abstract

    Normochromic or normocytic anaemia is a common side effect of treatment with cisplatin. Two patients treated with cisplatin 100 mg/m2 in combination with vinblastine, bleomycin, and actinomycin D developed haemolytic anaemia. Neither patient had evidence of haemolysis before treatment, and in both cases severe haemolytic anaemia developed after several courses of cisplatin and when the cancer had regressed almost completely. The importance of haemolysis in the development of anaemia after cisplatin treatment has not been investigated fully and further studies are needed.