Research Article

Thrombocytosis, circulating platelet aggregates, and neurological dysfunction.

Br Med J 1979; 2 doi: https://doi.org/10.1136/bmj.2.6204.1561 (Published 15 December 1979) Cite this as: Br Med J 1979;2:1561
  1. F E Preston,
  2. J F Martin,
  3. R M Stewart,
  4. G A Davies-Jones

    Abstract

    In 12 patients whose neurological dysfunction was associated with thrombocytosis or evidence of abnormal platelet activation, or both, correction of the platelet disorder corresponded with reversal of the neurological symptoms. This suggests that platelet abnormalities may, in certain cases, produce several syndromes of neurological dysfunction, presumably as a result of obstruction of the cerebral microcirculation.