O-diphenoloxidase concentrations in leprosy.Br Med J 1979; 2 doi: https://doi.org/10.1136/bmj.2.6195.900 (Published 13 October 1979) Cite this as: Br Med J 1979;2:900
- K Reza,
- S Talib,
- S K Imam
O-diphenoloxidase activity was studied in 15 patients with lepromatous leprosy, 15 with tuberculois leprosy, and 15 controls. O-diphenoloxidase isolated from skin and serum samples of patients with lepromatous leprosy had the specificity of a bacterially derived enzyme and not that of a mammalian-derived enzyme. Only the patients who had lepromatous leprosy for over two years showed enzyme activity in serum, though all showed it in skin tissue. O-diphenoloxidase activity in serum may be a useful diagnostic marker of lepromatous leprosy.