Research Article

Is your dosage really necessary? Antibiotic dosage in urinary infection.

Br Med J 1977; 2 doi: https://doi.org/10.1136/bmj.2.6088.665 (Published 10 September 1977) Cite this as: Br Med J 1977;2:665
  1. D Greenwood,
  2. F O'Grady

    Abstract

    Dense cultures of bacteria were exposed to changing concentrations of beta-lactam antibiotics in an in-vitro model of the urinary bladder. The results suggest that uncomplicated urinary infection may respond to lower doses than are usually given without compromising the success of subsequent treatment in those cases in which such minimal treatment fails.