Research Article

Hyposensitisation with house dust mite vaccine in bronchial asthma.

Br Med J 1976; 2 doi: https://doi.org/10.1136/bmj.2.6035.561 (Published 04 September 1976) Cite this as: Br Med J 1976;2:561

This article has a correction. Please see:

  1. J Gaddie,
  2. C Skinner,
  3. K N Palmer

    Abstract

    In a double-blind placebo-controlled trial of tyrosine-absorbed Dermatophagoides pteronyssinus vaccine no improvement was seen in 45 patients with asthma sensitive to house dust mite. In particular there was no significant improvement in symptom scores, spirometry, and skin and nasal challenge test results. Some patients in other studies have benefited from doses of vaccine much stronger than those now commercially available, but the incidence of side effects has also been high.