Research Article

Cushing's syndrome and pituitary-adrenal suppression due to clobetasol propionate.

Br Med J 1975; 2 doi: (Published 24 May 1975) Cite this as: Br Med J 1975;2:419
  1. R C Staughton,
  2. P J August


    Widespread application of clobetasol propionate resulted in suppression of the hypothalamic pituitary axis in four patients. Three patients showed Cushigoid features and developed symptoms of adrenocortical insufficiency on withdrawal of clobetasol.