Research Article

Comparison of two methods of administering bronchodilator aerosol to asthmatic patients.

Br Med J 1975; 2 doi: https://doi.org/10.1136/bmj.2.5963.119 (Published 19 April 1975) Cite this as: Br Med J 1975;2:119
  1. Y F Choo-Kang,
  2. I W Grant

    Abstract

    In 78 patients with chronic asthma the increase in forced expiratory volume in one second (FEV-1) after the administration by intermittent positive-pressure ventilation (I.P.P.V.) of 10 mg of salbutamol was compared with that recorded after the inhalation of a conventional dose (200 mug) from a pressurized canister. The mean increase was significantly greater after I.P.P.V. administration, and the superiority of this method was greatest in patients with the lowest pretreatment FEV-1.