Papers And Originals

Assessment of Coagulation and Fibrinolysis in Pre-eclampsia

Br Med J 1974; 2 doi: https://doi.org/10.1136/bmj.2.5911.145 (Published 20 April 1974) Cite this as: Br Med J 1974;2:145
  1. S. M. Wood,
  2. D. Burnett,
  3. A. M. Picken,
  4. G. W. Farrell,
  5. P. Wolf

    Abstract

    A method is described for distinguishing coagulation from fibrinolysis by three estimates of fibrinogen. This “fibrinogen series” together with plasma antithrombin and urinary urokinase have been compared in pregnant patients with venous thrombosis and pre-eclampsia. Evidence is presented for active coagulation during deterioration of the pre-eclampsia state and for enhanced fibrinolysis during improvement.