Papers And Originals

Clinical and Laboratory Double-blind Investigation on Effect of Fibrinolytic Therapy in Patients with Cutaneous Vasculitis

Br Med J 1973; 2 doi: https://doi.org/10.1136/bmj.2.5858.82 (Published 14 April 1973) Cite this as: Br Med J 1973;2:82

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  1. B. Dodman,
  2. W. J. Cunliffe,
  3. B. E. Roberts,
  4. R. Sibbald

    Abstract

    The effects of phenformin and ethyloestrenol and phenformin and stanozolol on the clinical state, plasma fibrinolytic activity, and fibrinogen-fibrin-related antigen (F.R.-antigen) were compared with placebo in 13 patients with cutaneous vasculitis. Eight patients showed considerable clinical improvement when taking phenformin and an anabolic steroid; an impaired fibrinolytic activity before treatment favoured clinical improvement.