Clinical and Laboratory Double-blind Investigation on Effect of Fibrinolytic Therapy in Patients with Cutaneous VasculitisBr Med J 1973; 2 doi: https://doi.org/10.1136/bmj.2.5858.82 (Published 14 April 1973) Cite this as: Br Med J 1973;2:82
- B. Dodman,
- W. J. Cunliffe,
- B. E. Roberts,
- R. Sibbald
The effects of phenformin and ethyloestrenol and phenformin and stanozolol on the clinical state, plasma fibrinolytic activity, and fibrinogen-fibrin-related antigen (F.R.-antigen) were compared with placebo in 13 patients with cutaneous vasculitis. Eight patients showed considerable clinical improvement when taking phenformin and an anabolic steroid; an impaired fibrinolytic activity before treatment favoured clinical improvement.