Relations between Blood Glucose and Hepatic Glucose Production in Newborn DogsBr Med J 1972; 2 doi: https://doi.org/10.1136/bmj.2.5814.625 (Published 10 June 1972) Cite this as: Br Med J 1972;2:625
- G. Hetenyi,
- S. Varma,
- J. S. Cowan
No correlation was found between the concentration of glucose in blood plasma and the rate of hepatic glucose production in newborn pups aged 2½-112 hours. During the first few hours of life the hypoglycaemic response to insulin was small or absent. Later the response seemed exaggerated mainly owing to a slow recovery to normoglycaemia. This latter observation can be entirely accounted for by the lack of a feedback mechanism between the plasma concentration and the hepatic rate of production of glucose.