Papers And Originals

Smoking in Pregnancy and Vitamin B12 Metabolism

Br Med J 1972; 2 doi: https://doi.org/10.1136/bmj.2.5805.74 (Published 08 April 1972) Cite this as: Br Med J 1972;2:74

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  1. John M. McGarry,
  2. Joan Andrews

    Abstract

    In pregnancy the level of serum vitamin B12 is lower in women who smoke than in non-smokers. This finding occurs independently of social class, parity, or level of haemoglobin. In addition, the mean serum B12 level tends to be less in women who are anaemic and is less in those women who have smaller babies. These findings may be an effect of the cyanide content of tobacco smoke, since cyanide may be detoxified by a mechanism which depletes the stores of vitamin B12 in the body.