Papers And Originals

Oedema in Rheumatoid Arthritis: Changes in the Coefficient of Capillary Filtration

Br Med J 1971; 2 doi: https://doi.org/10.1136/bmj.2.5761.555 (Published 05 June 1971) Cite this as: Br Med J 1971;2:555
  1. Malcolm I. V. Jayson,
  2. Jenny S. Barks

    Abstract

    The rate of formation of tissue fluid for a given increase of venous pressure and for a known volume of tissue has been measured in the forearm. There is a significant increase in this figure in rheumatoid arthritis and a still greater increase in patients who develop recurrent oedema. This increase could not be attributed to steroid or phenylbutazone therapy, nor to a fall in the serum albumin. The results imply that there is some generalized abnormality in capillary function in rheumatoid disease and that this change is not limited to the joints.