Papers And Originals

Response of Aspirin-Allergic Patients to Challenge by Some Analgesics in Common Use

Br Med J 1971; 2 doi: https://doi.org/10.1136/bmj.2.5760.494 (Published 29 May 1971) Cite this as: Br Med J 1971;2:494
  1. A. P. Smith

    Abstract

    Challenge tests with some analgesics in common use were performed in five aspirin-sensitive asthmatics. Marked falls in FEV1 were observed after ingestion of paracetamol, indomethacin, mefenamic acid, and dextropropoxyphene in some subjects. The mechanisms of analgesic-induced asthma are discussed: it is believed to be a non-immunological process of great practical importance when prescribing analgesics to asthmatics.