Papers And Originals

Controlled Trial of Metoclopramide in the Treatment of Flatulent Dyspepsia

Br Med J 1971; 2 doi: https://doi.org/10.1136/bmj.2.5752.25 (Published 03 April 1971) Cite this as: Br Med J 1971;2:25

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  1. A. G. Johnson

    Abstract

    A double-blind cross-over trial of metoclopramide (Maxolon) against placebo was undertaken in 42 patients with flatulent dyspepsia. A highly significant difference was found in favour of the active drug (P<0·01). The time at which the drug is given in relation to the meal and onset of symptoms is probably important. It is concluded that metoclopramide is effective in the short-term treatment of these symptoms but should be started only after thorough investigations have excluded more serious disease.