Papers And Originals

Autoimmunization with Irradiated Tumour Cells in Human Malignant Melanoma

Br Med J 1970; 2 doi: http://dx.doi.org/10.1136/bmj.2.5712.752 (Published 27 June 1970) Cite this as: Br Med J 1970;2:752

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  1. R. L. Ikonopisov,
  2. M. G. Lewis,
  3. I. D. Hunter-Craig,
  4. D. C. Bodenham,
  5. T. M. Phillips,
  6. C. I. Cooling,
  7. J. Proctor,
  8. G. Hamilton Fairley,
  9. P. Alexander

    Abstract

    Thirteen patients have been immunized with their own irradiated melanoma cells on one or more occasions. Following these autografts tumour-specific cytotoxic antibodies were produced, the longest response lasting 14 days. This procedure had no apparent effect on the course of the disease in these patients.