Papers And Originals

Nifuratel Compared with Metronidazole in the Treatment of Trichomonal Vaginitis

Br Med J 1970; 2 doi: https://doi.org/10.1136/bmj.2.5705.335 (Published 09 May 1970) Cite this as: Br Med J 1970;2:335
  1. B. A. Evans,
  2. R. D. Catterall

    Abstract

    Nifuratel (Magmilor) was compared with metronidazole (Flagyl) in the treatment of trichomonal vaginitis by a randomized double-blind trial. Only 18 out of 47 patients (38%) treated with nifuratel were found to be cured, whereas 42 out of 49 patients (85%) treated with metronidazole were cured. Severe reactions, necessitating withdrawal of treatment, occurred in three patients treated with nifuratel. There were no serious side-effects with metronidazole. The results of this trial indicate that nifuratel is not a satisfactory substitute for metronidazole in the treatment of trichomoniasis.