Regional Lung Function in Patients with Obstructive Lung DiseasesBr Med J 1970; 2 doi: https://doi.org/10.1136/bmj.2.5705.330 (Published 09 May 1970) Cite this as: Br Med J 1970;2:330
- Dominic Gaziano,
- Anthony Seaton,
- Colin Ogilvie
Regional lung function was measured, using radioactive xenon-133, in a group of normal subjects and in three carefully defined groups of patients with obstructive lung disease. When compared with the normal subjects, patients in the emphysematous group showed a relative reduction of ventilation and perfusion to the upper zones, while patients having chronic bronchitis without cardiac or respiratory failure showed a predominantly lower zone defect. In the group of patients with chronic bronchitis with cardiac and respiratory failure no consistent pattern was found.