Cephaloridine Serum Levels in Patients on Maintenance HaemodialysisBr Med J 1970; 2 doi: https://doi.org/10.1136/bmj.2.5702.149 (Published 18 April 1970) Cite this as: Br Med J 1970;2:149
- J. R. Curtis,
- Monica J. Marshall
Cephaloridine serum half-life was determined in 11 patients undergoing maintenance haemodialysis. Three of them were anephric. The mean cephaloridine half-life was 10·4 hours. There was an inverse correlation between cephaloridine half-life and the duration of maintenance haemodialysis treatment. Reasons for this are discussed.
The effect of haemodialysis with the Kiil dialyser on cephaloridine half-life was studied in three patients.
Dosage recommendations for patients on maintenance haemodialysis are suggested.