Papers And Originals

Cephaloridine Serum Levels in Patients on Maintenance Haemodialysis

Br Med J 1970; 2 doi: https://doi.org/10.1136/bmj.2.5702.149 (Published 18 April 1970) Cite this as: Br Med J 1970;2:149
  1. J. R. Curtis,
  2. Monica J. Marshall

    Abstract

    Cephaloridine serum half-life was determined in 11 patients undergoing maintenance haemodialysis. Three of them were anephric. The mean cephaloridine half-life was 10·4 hours. There was an inverse correlation between cephaloridine half-life and the duration of maintenance haemodialysis treatment. Reasons for this are discussed.

    The effect of haemodialysis with the Kiil dialyser on cephaloridine half-life was studied in three patients.

    Dosage recommendations for patients on maintenance haemodialysis are suggested.