Papers And Originals

Abnormalities of the Electrocardiogram in Female Carriers of Duchenne Muscular Dystrophy

Br Med J 1969; 2 doi: (Published 17 May 1969) Cite this as: Br Med J 1969;2:418
  1. A. E. H. Emery


    The algebraic sum of the R and S waves (R-S) in the V1 lead of the electrocardiogram has been found to be significantly greater in female carriers of X-linked Duchenne muscular dystrophy (but not in women with limb-girdle muscular dystrophy) compared with normal women of comparable age. A similar E.C.G. abnormality is found in affected boys, and possibly certain carriers have a latent cardiomyopathy and may even be predisposed to cardiac failure.