Pituitary Polypeptide with Hypoglycaemic Action in Diabetes MellitusBr Med J 1969; 2 doi: https://doi.org/10.1136/bmj.2.5650.157 (Published 19 April 1969) Cite this as: Br Med J 1969;2:157
- J. McD. Armstrong,
- J. Bornstein,
- F. M. Ng,
- H. P. Taft
A polypeptide isolated by the hydrolysis of growth hormone, studied in five patients with diabetes mellitus, has been shown able to produce hypoglycaemia, presumably by modifying the anti-insulin action of pituitary growth hormone. Possibly this substance may be suitable for treating cases of insulin resistance or when a circulating inhibitor of glucose uptake is present.