Research Article

Carcinoembryonic antigen in breast-cancer tissue: a useful prognostic indicator.

Br Med J 1979; 1 doi: https://doi.org/10.1136/bmj.1.6166.777 (Published 24 March 1979) Cite this as: Br Med J 1979;1:777
  1. S Shousha,
  2. T Lyssiotis,
  3. V M Godfrey,
  4. P J Scheuer

    Abstract

    Sections of breast carcinomas removed from 69 patients six to 13 years previously were examined using an immunoperoxidase technique to determine whether carcinoembryonic antigen (CEA) was present. Patients who had CEA-negative tumours had significantly higher five- and 10-year survival rates. The difference was not related to the stage of the disease, postoperative treatment, or histological type of tumour. These results suggest that immunohistological assessment of CEA in breast-cancer tissue may provide more precise prognostic information.