Research Article

Suspension of non-viable fungal spores as a standard for platelet counting.

Br Med J 1977; 1 doi: https://doi.org/10.1136/bmj.1.6067.1000 (Published 16 April 1977) Cite this as: Br Med J 1977;1:1000
  1. R K Archer,
  2. M Archer,
  3. B V Allen

    Abstract

    In the search among biological particles for a standard for counting human platelets, a strain of Absidia corymbifera was found to have spores that resembled platelets. After fixing in formalin and autoclaving the spores had a similar mean cell volume to that of human platelets. A suspension of these killed spores was tested in 100 laboratories and gave consistent results as a standard for human platelet counting. The Absidia corymbifera standard can be used in electronic counting methods but not in sedimentation methods, as the spores will be removed by centrifugation.