Research Article

Congenital malformation associated with intrauterine contraceptive device.

Br Med J 1976; 1 doi: (Published 28 February 1976) Cite this as: Br Med J 1976;1:488
  1. H Barrie


    Two infants with fibular aplasia and related limb-reduction defects were born to mothers who were using copper-containing intrauterine contraceptive devices. The possibility of a casual association is consistent with the known hazards of intrauterine devices and cannot be excluded on the available experimental evidence. More information is urgently needed, and searches, including radiography of placenta and pelvis, should be made for such devices in mothers who have used them in the past and who give birth to malformed infants.