Transmission of hepatitis type B from healthy HBsAg-positive mothers.Br Med J 1976; 1 doi: https://doi.org/10.1136/bmj.1.6000.10 (Published 03 January 1976) Cite this as: Br Med J 1976;1:10
- P Skinhoj,
- J Cohn,
- A F Bradburne
Seventeen mothers, all apparently healthy carriers of hepatitis-B surface antigen (HBsAg) during pregnancy, and their children were studied for four to five years to determine the transmission rate of hepatitis-B virus infection. All the mothers had antibody against hepatitis-B core antigen in addition to HBsAg. One of them, a renal transplant recipient, was persistently positive for hepatitis-B-associated e antigen (HBeAg), while the remaining 16, who were detected during screening of healthy pregnant women were positive for anti-HBe. Evidence of infection was found in the child and husband of the woman positive for HBeAg, while none of the 29 children and five husbands of the anti-HBe-positive women became infected.