Papers And Originals

Neuropathy Associated with Hepatitis in Patients Maintained on Haemodialysis

Br Med J 1972; 1 doi: http://dx.doi.org/10.1136/bmj.1.5797.409 (Published 12 February 1972) Cite this as: Br Med J 1972;1:409
  1. A. M. Davison,
  2. I. R. Williams,
  3. C. Mawdsley,
  4. J. S. Robson

    Abstract

    During a study of peripheral nerve function in chronic renal failure, 11 patients who were being treated by chronic intermittent haemodialysis developed serum hepatitis. Before the infection there was a trend towards improvement in nerve conduction velocities. A pronounced deterioration in the conduction velocities in motor fibres of peripheral nerves occurred in association with hepatitis. In the months after recovery from the infection there was again a trend towards improvement in conduction velocities. We suggest that this reflects the occurrence of a peripheral neuropathy which is at least in part demyelinating. The neuropathy is related to the serum hepatitis, but its pathogenesis is indeterminate.