Changes in Total Body Calcium and Sodium in OsteomalaciaBr Med J 1972; 1 doi: https://doi.org/10.1136/bmj.1.5791.19 (Published 01 January 1972) Cite this as: Br Med J 1972;1:19
- D. J. Hosking,
- M. J. Chamberlain,
- J. H. Fremlin,
- H. James
Serial measurements were made of total body calcium and sodium, using whole body neutron activation analysis, in six patients being treated for osteomalacia. All showed a rise in total body calcium ranging from 3 to 30%; this continued for up to 24 months after the start of treatment, though complete healing had apparently occurred after 6 months on the basis of histological examination of biopsy specimens of bone. As the total body calcium rose there was a fall in the non-exchangeable sodium pool in bone.