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Gross Oedema in the Nephrotic Syndrome Treated with Frusemide in High Dosage

Br Med J 1971; 1 doi: (Published 06 February 1971) Cite this as: Br Med J 1971;1:319

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  1. P. D. Snashall


    Five grossly oedematous patients with nephrotic syndrome required frusemide in doses of 250 mg/day or more. Two cases needed albumin infusions to initiate the diuresis. As oedema was removed renal function improved in four cases. There were no side effects. It is concluded that frusemide in the high doses used is a safe and effective diuretic.