Agglutinin Response to Pertussis Vaccination in the ChildBr Med J 1971; 1 doi: https://doi.org/10.1136/bmj.1.5740.86 (Published 09 January 1971) Cite this as: Br Med J 1971;1:86
- J. D. Abbott,
- N. W. Preston,
- R. I. Mackay
Children were immunized with plain pertussis vaccine made by three manufacturers in 1967. After a primary course of three injections at monthly intervals, starting at 3-4 months of age, the agglutinin response was poor. Even after a “booster” dose, given five months later, not all of the vaccines had stimulated a response to all three pertussis agglutinogens. A further investigation with current vaccines of different kinds administered according to more than one schedule is recommended.