Preliminary Communications

Urinary Hydroxyproline in the Elderly with Low Leucocyte Ascorbic Acid Levels

Br Med J 1970; 1 doi: http://dx.doi.org/10.1136/bmj.1.5698.732 (Published 21 March 1970) Cite this as: Br Med J 1970;1:732
  1. A. C. W. Windsor,
  2. C. B. Williams

    Abstract

    Fourteen elderly patients aged 58 to 91 with varying leucocyte ascorbic acid levels had urinary hydroxyproline/creatinine ratios measured before, during, and after treatment with ascorbic acid 1 g. daily for six days. The ratio increased during treatment in those patients whose initial ascorbic acid levels were below 15μg./108 white blood cells. It is suggested that collagen metabolism may be impaired in these patients, and that all such patients should receive ascorbic acid supplements.

    Sign in

    Log in through your institution

    Free trial

    Register for a free trial to thebmj.com to receive unlimited access to all content on thebmj.com for 14 days.
    Sign up for a free trial

    Subscribe