Papers And Originals

Practolol in Treatment of Supraventricular Cardiac Dysrhythmias

Br Med J 1970; 1 doi: (Published 28 February 1970) Cite this as: Br Med J 1970;1:533
  1. Graham Gent,
  2. Timothy C. Davis,
  3. Alastair McDonald


    Practolol (I.C.I. 50172) was used to treat supraventricular dysrhythmias in 32 patients with a rapid ventricular rate and with heart disease of varied aetiology. In 26 patients the average reduction in ventricular rate was 75 per minute, while immediate reversion to sinus rhythm occurred in three patients. The slowing effect was mainly due to a direct action on the atrioventricular node. The effectiveness of practolol was unrelated to the type of dysrhythmia or its aetiology. No serious adverse clinical effects were noted.