Papers And Originals

Younger Age of Presentation and Extraosseous Tumour in IgD Myelomatosis

Br Med J 1969; 1 doi: https://doi.org/10.1136/bmj.1.5641.412 (Published 15 February 1969) Cite this as: Br Med J 1969;1:412
  1. J. R. Hobbs,
  2. A. A. Corbett

    Abstract

    A study of 14 personal patients and 16 others in the literature shows that (1) IgD myelomatosis often presents at a significantly younger age than other forms of myelomatosis, and (2) during life extraosseous tumour can be detected in about two-thirds of these patients.

    The IgD form represents 1·5% of myelomatosis and shows an increased incidence of osteolytic lesions, hypercalcaemia, and renal failure, together with heavy Bence Jones proteinuria (90% type L).

    Like only Bence Jones myelomatosis, the IgD form seems to behave clinically in a more vicious manner.