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RESEARCH: Arash Afshari, Jørn Wetterslev, Jesper Brok, and Ann Møller Antithrombin III in critically ill patients: systematic review with meta-analysis and trial sequential analysis BMJ 2007; 0: bmj.39398.682500.25v1 [Abstract] [Full text]

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Heparin to stop bleeding after cardiopulmonary bypass

Friedrich Flachsbart   (16 December 2007)

Heparin to stop bleeding after cardiopulmonary bypass 16 December 2007
Friedrich Flachsbart, General Medicine Praxis 37085 Göttingen-Geismar Send response to journal: Re: Heparin to stop bleeding after cardiopulmonary bypass	Dear Sir, 1983 H. Koestering confirmed our 1981 observation of a prethrombotic state following the cardiopulmonary bypass in Göttingen. (1) Low-dose heparin in a very early moment of beginning low-grade- intravascular coagulation (renal and pulmonary complication) is the best. (2, 3) Heparin will guard against bleeding. Heparin will even stop bleeding. Best wishes Yours Friedrich Flachsbart 1. H Koestering: Antithrombin III: Grundlagen, Diagnostik, klinische Bedeutung und Therapie. Schattauer, Stuttgart, 1984 2. R Agarwal, D Gupta: Anticoagulation in sepsis: Is low-dose heparin as effective as activated protein C? Intensive Care Med (2005)31:1297-98 3. AD Cornet, EG Smit, A Beishuizen, AB Groeneveld: The role of heparin and allied compounds in the treatment of sepsis. Thromb Haemost (2007) 98:579-86 Competing interests: None declared