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RESEARCH:
Matejka Rebolj, Marjolein van Ballegooijen, Elsebeth Lynge, Caspar Looman, Marie-Louise Essink-Bot, Rob Boer, and Dik Habbema
Incidence of cervical cancer after several negative smear results by age 50: prospective observational study
BMJ 2009; 338: b1354 [Abstract] [Full text]
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Rapid Responses published:

[Read Rapid Response] Age is not a limiting factor for Cervical Cancer Screening
Dr Radhika Thangavelu   (25 April 2009)
[Read Rapid Response] The age factor
Dr Rajasree Pai   (28 April 2009)

Age is not a limiting factor for Cervical Cancer Screening 25 April 2009
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Dr Radhika Thangavelu,
SSHO
Royal Oldham Hospital, Oldham, Manchester

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Re: Age is not a limiting factor for Cervical Cancer Screening

Dear Sir, This Research article is quite interesting in view of the fact that even after 3 negative screening tests still the risk of cervical cancer is high and age beyond 50 has equivalent risk as young women. The recent celebrity demise has made many common people realise about the importance of regular and early cancer screening.Nevertheless incidence of cervical cancer is high due to screening and awareness. While reading in depth about pathophysiology of cervical cancer one would understand that dysplasia could occur due to mulltiple factors which is a harbinger to metaplasia and then to neoplasia.New treatment strategies coupled with government inteventions should improve cancer survival and to aim for better life. Thank you.

Competing interests: None declared

The age factor 28 April 2009
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Dr Rajasree Pai,
Resident
University of Connecticut

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Re: The age factor

It is not yet clear from the article whether serial screening with pap smear is beneficial or not as older women tend to have undergone longer periods of screening. The age factor is a crucial issue in cervical cancer as some studies point towards active sexual life and contraceptive pills as risk factors.

Competing interests: None declared