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EDITORIALS: Brian Sweeney Postoperative nausea and vomiting BMJ 2006; 333: 313-314 [Full text]

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Metoclpramide for nausea and vomiting

Giles W Stevenson   (14 August 2006)

Metoclpramide for nausea and vomiting 14 August 2006
Giles W Stevenson, Radiologist Cowichan District Hospital, Duncan, BC, Canada V9L5Y4 Send response to journal: Re: Metoclpramide for nausea and vomiting	Some years ago, one of my colleagues, pale, sweating and clearly hungover, made a bee line for the drug cupboard in the GI section of the radiology departmet and helped himself to 10mgm of oral Metoclopramide syrup. Within ten minutes his pallor disappeared and he became his normal efficient and sunny self. The nausea, and clammy pallor of the hangover, which can be less pleasantly relieved by vomiting, appear to be due to gastric dilatation associated with pylorospasm; and this small dose of metoclopramide, by allowing egress of a small amount of the toxic gastric contents, appears to take off sufficient pressure to relieve entirely this debilitating component of the hangover. I wonder if other readers have similar experience of this almost magically rapid healing effect of metoclopramide? Competing interests: None declared