Eileen McGinn, MPH New York New York 10003
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Re: Efficacy should drive atypical antipsychotic treatment
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People with schizophrenia have two to four times the rate of diabetes
as the general population, prior to any treatment with psychotropic drugs.
In addition, most studies show a similar effectiveness of typical and
atypical drugs. Atypicals are being promoted because of their benign
profile, which has to do with reduced EPS. Recent research has shown that
atypicals are associated with insulin resistance, etc. Their profile can
no longer be considered benign, but rather to have different concerns,
namely metabolic problems.
Competing interests:
None declared |