Rapid Responses to:

LETTERS:
Jane Logan
Haemoglobinopathy screening can be carried out in general practice
BMJ 2000; 320: 1542 [Full text]
*Rapid Responses: Submit a response to this article

Rapid Responses published:

[Read Rapid Response] We do it all the time
Luís Gomes   (3 June 2000)
[Read Rapid Response] Re: We do it all the time
Joseph Watine   (9 June 2000)

We do it all the time 3 June 2000
 Next Rapid Response Top
Luís Gomes
Algarve-Portugal

Send response to journal:
Re: We do it all the time

We are trying, in Portugal, to carry on an hemoglobinopathy screening for some years, now.

GPs ask for a blood test; the blood is sent to the regional health authority lab. Responses come in about two months...

As "mediterraneans", in Algarve we have a lot of Beta-talassemia minor.

That's why we are looking for it in pregnant women, young couples, suspected patients, patients relatives and african people.

Re: We do it all the time 9 June 2000
Previous Rapid Response  Top
Joseph Watine,
praticien hospitalier
Hôpital de Rodez, France

Send response to journal:
Re: Re: We do it all the time

Screening for thalassemia could easily and usefully be extented to some other at-risk groups of patients, using routine blood cell counts.

Indeed, in patients with low MCV (mean corpuscular volume), several indexes can easily be calculated, ENGLAND index for example (= MCV - (5 x Hb) - red cells - 3,4), where Hb is the blood hemoglobin concentration].
If the ENGLAND index is below –3, in a patient with a low MCV, then a screening test for thalassemia can be recommended.

In our laboratory medicine department, this is what we do, and this is how we regularly help in diagnosing thalassemic patients.

Joseph WATINE,
Laboratoire de biologie polyvalente, Centre Hospitalier Général, F-12027 Rodez Cédex 09, France
Email: j.watine@ch-rodez.fr