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Developing new policies from old evidence
| The first 150 words of the full text of this article appear below. |
Last week, the Department of Health in London published interim guidelines for responding to a deliberate release of smallpox in the United Kingdom. 1 2 The guidelines describe contingency plans for diagnosis and management of the first cases, vaccination strategies before and in the event of an outbreak, and other essential measures to ensure outbreak preparedness and control. Two of us (RH and DM) have contributed to the development of the guidelines, and the aim of this editorial is to give a brief summary and highlight some of the underlying evidence. (Comments on the guidelines may be sent to smallpoxplan@doh.gsi.gov.uk before the end of this year.)
Developing policies to combat an eradicated infectious disease is
difficult for two reasons. Firstly, it is impossible to balance the
benefits and risks of interventions against the potential risk from
disease. No one knows whether variola virus exists outside the two
laboratories approved by the World
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