Annex: Actually treated analysis

Table A Descriptive statistics by sex and intervention group at 16 month follow-up* (actually treated)

[Posted as supplied by the authors]

�	Comparison group		Condom Promotion intervention		*Condom promotion EC intervention**
�	Women	Men	Women	Men	Women	Men
Sex	�	46% (43% - 49%)	�	43% (34% - 51%)	�	44% (40% - 48%)
N	�	998	�	987	�	1320
Age	16.72 (16.65 - 16.80)	16.79 (16.64 - 16.95)	16.85 (16.76 - 16.93)	16.89 (16.77 - 17.02)	16.73 (16.66 - 16.80)	16.91 (16.79 - 17.03)
N	1151	973	1263	942	1640	1257
Significant other	45% (39% - 50%)	37% (34% - 40%)	53% (50% - 56%)	39% (35% - 44%)	46% (44% - 49%)	38% (35% - 41%)
N	1153	959	1277	952	1648	1281
Age of significant other	18.77 (18.38 - 19.17)	17.08 (16.82 - 17.33)	19.12 (18.66 - 19.57)	16.95 (16.71 - 17.20)	18.98 (18.72 - 19.24)	16.89 (16.77 - 17.01)
N	506	354	668	370	752	481
HIV Knowledge	40.54 (39.83 - 41.25)	40.15 (39.50 - 40.79)	40.90 (40.56 - 41.24)	40.67 (40.27 - 41.08)	41.58 (41.16 - 41.99)	41.22 (40.69 - 41.74)
N	1160	971	1302	964	1649	1299
EC Knowledge	63% (57% - 69%)	61% (56% - 66%)	60% (55% - 66%)	60% (54% - 65%)	83% (78% - 87%)	77% (72% - 83%)
N	1099	898	1238	899	1584	1213
Would use condom	74% (68% - 81%)	57% (52% - 63%)	75% (72% - 79%)	57% (53% - 60%)	81% (77% - 84%)	58% (53% - 63%)
N	628	660	756	644	980	895
Would stop sex to wear a condom	93% (91% - 94%)	81% (77% - 84%)	93% (92% - 95%)	83% (80% - 86%)	94% (92% - 96%)	82% (78% - %86)
N	853	787	978	785	1343	1052
Would condition sex on condom use	98% (97% - 99%)	91% (89% - 93%)	98% (96% - 99%)	92% (90% - 93%)	98% (97% - 99%)	93% (91% - 95%)
N	1012	779	1111	755	1469	1051
Sexually active	18% (15% - 21%)	27% (24% - 31%)	18% (15% - 21%)	27% (22% - 32%)	16% (13% - 19%)	29% (26% - 33%)
N	1137	939	1268	919	1626	1247

*Adjusted for cluster design using an estimation that identify schools as primary sampling units. Numbers in bold indicate a 95% significant difference between intervention group(s) with the comparison group; number in italics indicate a 95% significant difference between men and women within the group (intervention A, B or comparison).

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Table B Descriptive statistics by sex and intervention group for sexually active students* (actually treated)

[Posted as supplied by authors]

�	Comparison group		Condom Promotion intervention		Condom Promotion + EC intervention
�	Women	Men	Women	Men	Women	Men
Condom use at first intercourse	41% (30% - 52%)	39% (35% - 43%)	47% (43% - 50%)	40% (34% - 46%)	56% (50% - 62%)	40% (33% - 46%)
N	201	255	224	246	256	357
Condom use at last intercourse	42% (33% - 50%)	49% (42% - 55%)	46% (41% - 52%)	51% (44% - 57%)	48% (42% - 54%)	50% (44% - 56%)
N	200	245	219	245	255	349
Sexual intercourse with sex worker, casual partner or compensated sex	3% (2% - 5%)	30% (24% - 37%)	11% (3% - 18%)	36% (33% - 40%)	6% (4% - 9%)	33% (28% - 38%)
N	126	206	141	196	164	287
Condom use with sex worker, casual partner or compensated sex	75% (31% - 119%)	69% (61% - 78%)	67% (50% - 84%)	80% (68% - 93%)	50% (21% - 79%)	85% (81% - 90%)
N	4	62	15	71	10	95
Used emergency contraception	22% (16% - 29%)	15% (10% - 20%)	22% (17% - 27%)	21% (16% - 25%)	35% (28% - 42%)	21% (16% - 25%)
N	201	238	219	233	256	341
Positive to HSV 2 antibodies	23% (5% - 42%)	17% (0% - 34%)	32% (24% - 39%)	29% (19% - 40%)	17% (4% - 29%)	12% (0% - 23%)
N	158	170	208	215	223	276
Had an older sexual partner	23% (16% - 29%)	22% (18% - 27%)	33% (26% - 39%)	29% (23% - 35%)	31% (28% - 35%)	23% (19% - 27%)
N	191	234	205	222	245	324
Had experience condom slippage	32% (24% - 39%)	32% (27% - 37%)	21% (12% - 31%)	31% (25% - 37%)	23% (17% - 28%)	33% (29% - 36%)
N	149	186	160	179	204	280
Had experience condom breakage	22% (12% - 31%)	16% (11% - 20%)	15% (9% - 20%)	19% (14% - 24%)	14% (9% - 20%)	16% (11% - 21%)
N	148	185	161	184	204	284

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Table C Multivariate logistic regression to estimate impact of intervention on selected outcome variables (actually treated analysis, fixed effect models to correct for cluster design) [Posted as supplied by authors]

�	HIV Knowledge*	EC Knowledge	Would use condom	Would stop sex to wear a condom	Condom use at first intercourse	Condom use at last intercourse	Had used EC
Intervention CP = 1	1.25 (0.96 � 1.55)	1.13 (0.96 - 1.34)	1.17 (0.92 - 1.48)	1.40 (1.07 - 1.84)	1.22 (0.83 - 1.78)	1.17 (0.80 - 1.70)	1.01 (0.62 - 1.65)
Intervention CP+EC = 1	1.15 (0.86 � 1.43)	2.90 (2.44 - 3.44)	1.00 (0.80 - 1.26)	1.16 (0.90 - 1.50)	1.12 (0.78 - 1.61)	1.05 (0.73 - 1.51)	1.91 (1.19 - 3.08)
Follow-up = 1	1.54 (1.32 � 1.75)	2.45 (2.17 - 2.76)	1.66 (1.40 - 1.97)	1.33 (1.10 - 1.61)	1.02 (0.77 - 1.34)	0.71 (0.54 - 0.93)	1.07 (0.74 - 1.54)
Male = 1	-0.10 (-0.22 � 0.01)	0.98 (0.91 - 1.05)	0.53 (0.48 - 0.58)	0.43 (0.39 - 0.48)	0.83 (0.71 - 0.97)	1.43 (1.22 - 1.67)	0.72 (0.60 - 0.88)
Age at baseline	-0.06 (-0.13 � 0.01)	1.01 (0.97 - 1.06)	0.93 (0.88 - 0.98)	1.04 (0.97 - 1.10)	0.95 (0.88 - 1.03)	0.90 (0.84 - 0.97)	0.94 (0.85 - 1.04)
Ever sexually active = 1	0.52 (0.37 � 0.67)	1.45 (1.33 - 1.59)	0.66 (0.60 - 0.74)	0.76 (0.67 - 0.85)	na⁺	na⁺	na⁺
N	16708	16129	8226	12220	3024	2985	2871
Prob > Chi²	0.0000	0.0000	0.0000	0.0000	0.0214	0.0000	0.0000

Results in bold are significant at 95%. ⁺ not applicable because these models only include sexually active participants

*This dependent variable (HIV knowledge index) is treated as a continuous variable 0-36 and is therefore the only regression that is not logistic (and therefore significance is measure as a value different from 0), and instead of Chi2, it refers to a F test.

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