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Appendix Table A. Metabolic Syndrome Criteria Fulfilled at Ages 50 and 70 in the Total Sample

Age			50		70
Metabolic syndrome criteria	NCEP criteria	WHO criteria	NCEP_BMI	WHO_HOMA	NCEP_WAIST	NCEP_BMI	WHO_CLAMP	WHO_HOMA
Subjects with metabolic syndrome, n			405	270	294	282	520	258
Impaired glucose metabolism	Fasting p-glucose ≥6.1 mmol/l	IGT, IFG or diabetes mellitus and/or insulin resistance	206 (51)	219 (100)	146 (50)	146 (52)	520 (100)	258 (100)
Hypertension	Blood pressure ≥130/85 mmHg or Rx	Blood pressure ≥140/90 mmHg or Rx	385 (95)	259 (96)	288 (98)	277 (98)	468 (90)	250 (97)
Dyslipidemia	Triglycerides ≥1.7 mmol/l	Triglycerides ≥1.7 mmol/l and/or HDL cholesterol <0.91 mmol/l	387 (96)	259 (96)	215 (73)	210 (74)	246 (47)	202 (78)
Dyslipidemia	HDL cholesterol <1.04 mmol/l		210 (52)	259 (96)	191 (65)	183 (65)	246 (47)	202 (78)
Central obesity	BMI>29.4 kg/m²	Waist/hip ratio >0.9 and/or BMI >30 kg/m²	142 (35)	87 (32)	-	139 (49)	490 (94)*	121 (47)
Central obesity	Waist circumference >102 cm	Waist/hip ratio >0.9 and/or BMI >30 kg/m²	-	87 (32)	145 (49)	-	490 (94)*	121 (47)
Target organ damage	-	Microalbuminuria (urinary albumin excretion rate ≥20 �g/min)	-	-	-	-	116 (22)	-

Data are numbers of individuals (percent) fulfilling the metabolic syndrome criteria according to the various definitions. *, For ease of comparison between the two ages, the modified WHO_HOMA definitions are identical at ages 50 and 70, but the WHO_CLAMP definition at age 70 also includes the waist/hip ratio and microalbuminuria criteria (see Table 1). NCEP, National Cholesterol Education Program; WHO, World Health Organisation; HOMA, homeostasis model assessment; IGT, impaired glucose tolerance; IFG, impaired fasting glucose; Rx, treatment; HDL, high-density lipoprotein; BMI, body mass index.