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Other members of the WHO-CHOICE MDG team are Rob Baltussen, Dan Chisholm, Benjamin Johns, Jeremy A Lauer, and Joshua A Salomon.
Table A Conversion factors for a typical country in each region - International dollars to US dollars, year 2000.
|
Region |
Country |
Purchasing power parity exchange rate |
Official exchange rate |
Conversion factor |
|
(1) |
(2) |
(3) = (1)*(2) |
||
|
Afr-E |
Kenya |
17.10 |
0.013 |
0.22 |
|
Sear-D |
India |
8.65 |
0.022 |
0.19 |
Published as supplied by the authors
Table B. Annual costs, effects and cost-effectiveness of excluded or "dominated" interventions
|
MDG Target Group |
Intervention (coverage) |
Average yearly cost (millions $Int) |
Average yearly DALYs averted (millions) |
Average cost-effectiveness ratio (ACER) |
|
Afr-E |
||||
|
Malaria |
Case management with chloroquine-sulfadoxine-pyrimethamine combination treatment (95%)* |
72 |
4.48 |
17 |
|
Malaria |
Case management with sulfadoxine-pyrimethamine (95%)* |
72 |
4.11 |
29 |
|
Malaria |
Case management with chloroquine (95%)* |
72 |
2.50 |
41 |
|
Under 5s |
Complementary feeding (95%)** |
3,334 |
0.08 |
42,680 |
|
Sear-D |
||||
|
Under 5s |
Complementary feeding (95%)** |
7,684 |
0.58 |
13,206 |
|
*Dominated by case management with artemisinin-based combination
therapy. |
||||
Published as supplied by the author
Table C: Annual costs, effects and cost-effectiveness of non-dominated interventions for Afr-E to achieve health-related MDGs.
|
No. |
Goal |
Intervention (coverage) |
Incremental yearly cost (millions $Int) |
Incremental yearly DALYs averted (millions) |
Incremental cost effectiveness ratio ($Int/DALY averted) |
|
Highly cost-effective interventions* |
|
|
|
||
|
A1 |
Maternal and neonatal health |
Community-based case management for neonatal pneumonia (95%) |
1 |
1.45 |
1 |
|
A2 |
HIV and AIDS |
Mass media campaign to promote safer sex (100%) |
16 |
4.54 |
3 |
|
A3 |
HIV and AIDS |
Peer education and treatment of sexually transmitted infections for sex workers (50%) |
42 |
11.07 |
4 |
|
A4 |
HIV and AIDS |
Peer education and treatment of sexually transmitted infections for sex workers (expanded to 80%) |
22 |
5.65 |
4 |
|
A5 |
HIV and AIDS |
Peer education and treatment of sexually transmitted infections for sex workers (expanded to 95%) |
10 |
2.56 |
4 |
|
A6 |
Tuberculosis |
Treatment of new smear-positive TB cases only under DOTS (50%) |
146 |
23.56 |
6 |
|
A7 |
Maternal and neonatal health |
Community newborn package (95%): |
57 |
7.10 |
8 |
|
A8 |
Tuberculosis |
Treatment of new smear-positive TB cases only under DOTS (expanded to 80%) |
116 |
14.14 |
8 |
|
A9 |
Malaria |
Case management of malaria with artemisinin based combination treatment (95%) |
73 |
5.89 |
12 |
|
A10 |
Tuberculosis |
Treatment of new smear-positive tuberculosis cases only under DOTS (expanded to 95%) |
104 |
7.07 |
15 |
|
A11 |
Under 5s |
Vitamin A fortification of food staple (95%) |
23 |
1.20 |
19 |
|
A12 |
Maternal and neonatal health |
Tetanus toxoid (95%) |
67 |
3.06 |
22 |
|
A13 |
HIV and AIDS |
Prevention of mother-to-child transmission (ANC coverage) |
82 |
3.47 |
27 |
|
A14 |
Maternal and neonatal health |
Screening for pre-eclampsia (95%) |
35 |
1.28 |
29 |
|
A15 |
Under 5s |
Measles vaccination (80%) |
5 |
0.17 |
40 |
|
A16 |
Maternal and neonatal health |
Normal delivery by skilled attendant (95%) |
124 |
3.06 |
42 |
|
A17 |
Maternal and neonatal health |
Treatment of severe pre-eclampsia/eclampsia (95%) |
22 |
0.53 |
46 |
|
A18 |
Malaria |
Insecticide treated bed nets (95%) |
182 |
3.25 |
56 |
|
A19 |
Under 5s |
Measles vaccination (exapnded to 95%) |
2 |
0.03 |
58 |
|
A20 |
Maternal and neonatal health |
Facility-based care of very low birth weight babies, severe neonatal infections, severe neonatal asphyxia and neonatal jaundice (95%) |
192 |
3.15 |
61 |
|
A21 |
HIV and AIDS |
Treatment of sexually transmitted infections (current coverage) |
41 |
0.60 |
68 |
|
A22 |
Under 5s |
Case management for childhood pneumonia (80%) |
170 |
2.34 |
73 |
|
A23 |
Maternal and neonatal health |
Management of obstructed labour, breech and fetal distress (95%) |
91 |
1.25 |
73 |
|
A24 |
HIV and AIDS |
Treatment of sexually transmitted infections (expanded to ANC coverage) |
67 |
0.84 |
80 |
|
A25 |
Under 5s |
Vitamin A supplementation (80%, replaces fortification) |
125 |
1.47 |
85 |
|
A26 |
Tuberculosis |
Treatment of smear-negative tuberculosis cases under DOTS (95%) |
246 |
2.60 |
94 |
|
A27 |
Under 5s |
Oral rehydration therapy for diarrhoea (80%) |
386 |
3.65 |
106 |
|
A28 |
Maternal and neonatal health |
Antenatal steroids for pre-term births (95%) |
117 |
1.00 |
117 |
|
A29 |
Malaria |
Indoor residual spraying (95%) |
186 |
1.58 |
118 |
|
A30 |
Tuberculosis |
Treatment of multi-drug resistant tuberculosis under DOTS-Plus (95%) |
127 |
1.03 |
123 |
|
A31 |
Maternal and neonatal health |
Management of maternal sepsis (95%) |
42 |
0.33 |
125 |
|
A32 |
Malaria |
Intermittent presumptive treatment during pregnancy (95%) |
1 |
0.01 |
151 |
|
A33 |
Maternal and neonatal health |
Antibiotics for pre-term premature rupture of membranes (95%) |
34 |
0.19 |
178 |
|
A34 |
HIV and AIDS |
Voluntary counseling and testing (95%) |
385 |
1.75 |
220 |
|
A35 |
Maternal and neonatal health |
Referral care for severe post-partum haemorrhage (95%) |
19 |
0.09 |
223 |
|
A36 |
Under 5s |
Vitamin A Supplementation (expanded to 95%) |
395 |
1.62 |
243 |
|
A37 |
HIV and AIDS |
Treatment of sexually transmitted infections (expanded to 95%) |
117 |
0.40 |
290 |
|
A38 |
HIV and AIDS |
Antiretroviral therapy: no intensive monitoring, first-line drugs only (95%) |
1,266 |
2.32 |
547 |
|
A39 |
HIV and AIDS |
School-based education on safer sex (95%) |
77 |
0.12 |
631 |
|
A40 |
HIV and AIDS |
Antiretroviral therapy: intensive monitoring, first-line drugs only (95%) |
148 |
0.13 |
1,144 |
|
Not cost-effective interventions† |
|
|
|
||
|
A41 |
HIV and AIDS |
Antiretroviral therapy: intensive monitoring, first- and second-line drugs (95%) |
5,133 |
0.99 |
5,175 |
|
A42 |
Under 5s |
Improved complementary feeding, growth monitoring and promotion (95%) |
1,630 |
0.13 |
12,791 |
|
|
|
|
|
|
|
*Highly cost-effective if ICER ≤ Int$1,576
†Not cost-effective if ICER > Int$4,728
Posted as supplied by the author
Table D: Annual costs, effects and cost-effectiveness of non-dominated interventions for Sear-D to achieve health-related MDGs.
|
No. |
Goal |
Intervention (coverage) |
Incremental yearly cost (millions $Int) |
Incremental yearly DALYs averted (millions) |
Incremental cost-effectiveness ratio ($Int/DALY averted) |
|
Highly cost-effective interventions* |
|
|
|
||
|
B1 |
HIV and AIDS |
Peer education and treatment of sexually transmitted infections for sex workers (50%) |
83 |
29.93 |
3 |
|
B2 |
HIV and AIDS |
Peer education and treatment of sexually transmitted infections for sex workers (expanded to 80%) |
39 |
12.12 |
3 |
|
B3 |
HIV and AIDS |
Peer education and treatment of sexually transmitted infections for sex workers (expanded to 95%) |
19 |
4.54 |
4 |
|
B4 |
Maternal and neonatal health |
Community-based support for breastfeeding mothers (50%) |
49 |
8.50 |
6 |
|
B5 |
Maternal and neonatal health |
Community-based support for breastfeeding mothers (expanded to 80%) |
31 |
5.10 |
6 |
|
B6 |
Tuberculosis |
Treatment of new smear-positive tuberculosis cases only under DOTS (80%) |
443 |
64.52 |
7 |
|
B7 |
Maternal and neonatal health |
Community-based support for breastfeeding mothers (expanded to 95%) |
18 |
2.55 |
7 |
|
B8 |
Maternal and neonatal health |
Tetanus toxoid (80%) |
57 |
7.48 |
8 |
|
B9 |
Tuberculosis |
Treatment of new smear-positive tuberculosis cases only under DOTS (expanded to 95%) |
94 |
12.10 |
8 |
|
B10 |
Maternal and neonatal health |
Tetanus toxoid (expanded to 95%) |
39 |
4.43 |
9 |
|
B11 |
Under 5s |
Zinc fortification of food staple (95%) |
12 |
0.90 |
14 |
|
B12 |
Maternal and neonatal health |
Community-based support for low birth weight babies (95%) |
1 |
0.06 |
20 |
|
B13 |
HIV and AIDS |
Mass media campaign to promote safer sex (100%) |
33 |
0.66 |
51 |
|
B14 |
Tuberculosis |
Treatment of smear-negative tuberculosis cases under DOTS (95%) |
347 |
6.73 |
52 |
|
B15 |
Under 5s |
Vitamin A fortification of food staple (95%) |
37 |
0.53 |
70 |
|
B16 |
Under 5s |
Case management for childhood pneumonia (80%) |
316 |
4.26 |
74 |
|
B17 |
Maternal and neonatal health |
Normal delivery by skilled attendant (95%) |
231 |
2.62 |
88 |
|
B18 |
Under 5s |
Case management for childhood pneumonia (expanded to 80%) |
105 |
1.07 |
99 |
|
B19 |
Under 5s |
Measles vaccination (95%) |
14 |
0.14 |
102 |
|
B20 |
Maternal and neonatal health |
Screening for pre-eclampsia (95%) |
49 |
0.40 |
123 |
|
B21 |
HIV and AIDS |
Treatment of sexually transmitted infections (95%) |
336 |
2.53 |
133 |
|
B22 |
Maternal and neonatal health |
Community-based case management for neonatal pneumonia (95%) |
9 |
0.06 |
144 |
|
B23 |
Under 5s |
Zinc supplementation (95%, replaces fortification) |
951 |
6.00 |
158 |
|
B24 |
Maternal and neonatal health |
Neonatal resucitation (95%) |
52 |
0.24 |
218 |
|
B25 |
Tuberculosis |
Treatment of multi-drug resistant tuberculosis under DOTS-Plus (95%) |
389 |
1.72 |
226 |
|
B26 |
Maternal and neonatal health |
Referral care for severe post-partum haemorrhage (95%) |
34 |
0.13 |
261 |
|
B27 |
Maternal and neonatal health |
Management of maternal sepsis (95%) |
83 |
0.29 |
290 |
|
B28 |
HIV and AIDS |
Voluntary counseling and testing (95%) |
182 |
0.57 |
317 |
|
B29 |
Under 5s |
Vitamin A supplementation (95%, replaces fortification) |
534 |
1.53 |
350 |
|
B30 |
HIV and AIDS |
Prevention of mother-to-child transmission (ANC coverage) |
155 |
0.31 |
614 |
|
B31 |
Maternal and neonatal health |
Facility-based care of very low birth weight babies, severe neonatal infections, severe neonatal asphyxia and neonatal jaundice (95%) |
385 |
0.63 |
699 |
|
B32 |
HIV and AIDS |
Screening & treatment of syphillis (95%) |
9 |
0.01 |
760 |
|
B33 |
Maternal and neonatal health |
Antiretroviral therapy: no intensive monitoring, first-line drugs only (95%) |
456 |
0.60 |
850 |
|
B34 |
HIV and AIDS |
Antiretroviral therapy: intensive monitoring, first-line drugs only (95%) |
27 |
0.02 |
1,295 |
|
Cost-effective interventions† |
|
|
|
||
|
B35 |
HIV and AIDS |
School-based education (95%) |
176 |
0.08 |
2,192 |
|
B36 |
Maternal and neonatal health |
Management of obstructed labour, breech and fetal distress (95%) |
186 |
0.07 |
2,638 |
|
B37 |
Maternal and neonatal health |
Antibiotics for pre-term premature rupture of membranes (95%) |
65 |
0.02 |
2,808 |
|
Not cost-effective interventions‡ |
|
|
|
||
|
B38 |
HIV and AIDS |
Antiretroviral therapy: intensive monitoring, first- and second-line drugs (95%) |
861 |
0.20 |
4,406 |
|
B39 |
Maternal and neonatal health |
Antenatal steroids for pre-term births (95%) |
319 |
0.02 |
16,930 |
|
B40 |
Under 5s |
Improved complementary feeding, growth monitoring and promotion (95%) |
4,452 |
0.10 |
44,384 |
|
|
|
|
|
|
|
*Highly cost-effective if ICER ≤ Int$1,449
†Cost-effective if ICER > Int$1,449 and ≤ Int$4,347
‡Not cost-effective if ICER > Int$4,347