Table A

Table B

Annex A

 

Table A: [As supplied by authors] Costs, effectiveness and cost-effectiveness ratios of all interventions and combinations for Afr-E in 2000 international dollars

                   

No.

Description of intervention

Yearly Costs (millions Int$)

Yearly DALYs averted (millions)

ACER (I$ per DALY averted)

ICER (I$ per DALY averted)

 

 

 

 

                   

1

Oral Rehydration Therapy (ORT) (@50%)

$237

2.18

$109

Dominated

       

2

Oral Rehydration Therapy (@80%)

$422

3.48

$121

Dominated

       

3

Oral Rehydration Therapy (@95%)

$577

4.14

$139

Dominated

       

4

Case management for childhood pneumonia (CM) (@50%)

$94

1.52

$62

Dominated

       

5

Case management for childhood pneumonia (@80%)

$174

2.43

$72

Dominated

       

6

Case management for childhood pneumonia (@95%)

$249

2.88

$87

Dominated

       

7

Vitamin A supplementation (@50%)

$26

0.51

$52

Dominated

       

8

Vitamin A supplementation (@80%)

$136

0.81

$168

Dominated

       

9

Vitamin A supplementation (@95%)

$250

0.96

$260

Dominated

       

10

Vitamin A fortification (@50%)

$10

0.24

$41

Dominated

       

11

Vitamin A fortification (@80%)

$13

0.38

$34

Dominated

       

12

Vitamin A fortification (@95%)

$14

0.45

$32

Dominated

       

13

Provision of supplementary food and nutrition counselling (SF) (@50%)

$1,741

0.04

$42,340

Dominated

       

14

Provision of supplementary food and nutrition counselling (@80%)

$2,793

0.07

$42,460

Dominated

       

15

Provision of supplementary food and nutrition counselling (@95%)

$3,334

0.08

$42,680

Dominated

       

16

Provision of supplementary food and nutrition counselling with growth monitoring (SFGM) (@50%)

$918

0.04

$22,320

Dominated

       

17

Provision of supplementary food and nutrition counselling with growth monitoring @80%)

$1,476

0.07

$22,428

Dominated

       

18

Provision of supplementary food and nutrition counselling with growth monitoring @95%)

$1,769

0.08

$22,649

Dominated

       

19

Zinc supplementation (@50%)

$20

0.16

$120

Dominated

       

20

Zinc supplementation (@80%)

$31

0.26

$117

Dominated

       

21

Zinc supplementation (@95%)

$38

0.31

$122

Dominated

       

22

Zinc fortification (@50%)

$7

0.08

$82

Dominated

       

23

Zinc fortification (@80%)

$8

0.13

$60

Dominated

       

24

Zinc fortification (@95%)

$9

0.16

$55

Dominated

       

25

ORT & CM (@50%)

$307

3.72

$83

Dominated

       

26

ORT & CM (@80%)

$552

5.95

$93

Dominated

       

27

ORT & CM (@95%)

$765

7.07

$108

Dominated

       

28

Vit A. Fort. & Zinc Fort. (@50%)

$15

0.63

$24

Dominated

       

29

Vit A. Fort. & Zinc Fort. (@80%)

$20

1.01

$20

Dominated

       

30

Vit A. Fort. & Zinc Fort. (@95%)

$23

1.20

$19

$19

       

31

Zinc Fort & CM (@50%)

$109

1.67

$66

Dominated

       

32

Zinc Fort & CM (@80%)

$194

2.66

$73

Dominated

       

33

Zinc Fort & CM (@95%)

$272

3.16

$86

Dominated

       

34

Vit. A Suppl. & Zinc Suppl. (@50%)

$95

1.55

$61

Dominated

       

35

Vit. A Suppl. & Zinc Suppl. (@80%)

$180

2.47

$73

Dominated

       

36

Vit. A Suppl. & Zinc Suppl. (@95%)

$265

2.94

$90

Dominated

       

37

Zinc Suppl. & Zinc Fort (@50%)

$48

0.14

$341

Dominated

       

38

Zinc Suppl. & Zinc Fort (@80%)

$78

0.22

$348

Dominated

       

39

Zinc Suppl. & Zinc Fort (@95%)

$104

0.27

$391

Dominated

       

40

Vit. A Fort., Zinc Fort.& ORT (@50%)

$252

2.82

$89

Dominated

       

41

Vit. A Fort., Zinc Fort.& ORT (@80%)

$441

4.51

$98

Dominated

       

42

Vit. A Fort., Zinc Fort.& ORT (@95%)

$598

5.35

$112

Dominated

       

43

Vit. A Fort., Zinc Fort. & CM (@50%)

$109

2.21

$49

Dominated

       

44

Vit. A Fort., Zinc Fort. & CM (@80%)

$194

3.54

$55

Dominated

       

45

Vit. A Fort., Zinc Fort. & CM (@95%)

$272

4.20

$65

Dominated

       

46

Zinc Fort., ORT & CM (@50%)

$313

3.87

$81

Dominated

       

47

Zinc Fort., ORT & CM (@80%)

$560

6.19

$90

Dominated

       

48

Zinc Fort., ORT & CM (@95%)

$881

7.35

$120

Dominated

       

49

Zinc Suppl., ORT & CM (@50%)

$328

3.97

 

Dominated

       

50

Zinc Suppl., ORT & CM (@80%)

$588

6.35

$92

Dominated

       

51

Zinc Suppl., ORT & CM (@95%)

$812

7.55

$108

Dominated

       

52

Vit. A Suppl., Zinc Suppl., & CM (@50%)

$170

3.13

$54

Dominated

       

53

Vit. A Suppl., Zinc Suppl., & CM (@80%)

$319

5.01

$64

Dominated

       

54

Vit. A Suppl., Zinc Suppl., & CM (@95%)

$466

5.95

$78

Dominated

       

55

Vit. A Suppl., Zinc Suppl., & ORT (@50%)

$313

3.72

$84

Dominated

       

56

Vit. A Suppl., Zinc Suppl., & ORT (@80%)

$567

5.96

$95

Dominated

       

57

Vit. A Suppl., Zinc Suppl., & ORT (@95%)

$793

7.08

$112

Dominated

       

58

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%)

$386

5.41

$71

Dominated

       

59

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%)

$705

8.66

$81

Dominated

       

60

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%)

$1,099

10.28

$107

Dominated

       

61

Vit. A Fort., Zinc Fort., ORT & CM (@50%)

$321

4.45

$72

Dominated

       

62

Vit. A Fort., Zinc Fort., ORT & CM (@80%)

$571

7.12

$80

Dominated

       

63

Vit. A Fort., Zinc Fort., ORT & CM (@95%)

$786

8.46

$93

Dominated

       

64

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%)

$110

0.74

$150

Dominated

       

65

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%)

$200

1.18

$170

Dominated

       

66

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%)

$288

1.40

$206

Dominated

       

67

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%)

$1,289

5.48

$235

Dominated

       

68

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%)

$2,157

8.77

$246

Dominated

       

69

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%)

$2,730

10.41

$262

Dominated

       

70

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%)

$1,224

4.48

$273

Dominated

       

71

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%)

$2,022

7.17

$282

Dominated

       

72

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%)

$2,632

8.52

$309

Dominated

       

73

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%)

$185

2.32

$80

Dominated

       

74

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%)

$339

3.71

$91

Dominated

       

75

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%)

$489

4.41

$111

Dominated

       

76

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%)

$401

4.56

$88

Dominated

       

77

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%)

$725

7.29

$99

Dominated

       

78

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%)

$1,123

8.66

$130

Dominated

       

79

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%)

$1,303

4.59

$284

Dominated

       

80

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%)

$2,175

7.35

$296

Dominated

       

81

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%)

$2,859

8.73

$327

Dominated

       

82

Vit A. Fort. & Zinc Fort. (@50%) + Measles immunisation (@50%)

$50

1.69

$30

Dominated

       

83

Vit A. Fort. & Zinc Fort. (@80%) + Measles immunisation (@50%)

$56

2.07

$27

Dominated

       

84

Vit A. Fort. & Zinc Fort. (@95%) + Measles immunisation (@50%)

$59

2.26

$26

Dominated

       

85

Zinc Fort & CM (@50%) + Measles immunisation (@50%)

$145

2.73

$53

Dominated

       

86

Zinc Fort & CM (@80%) + Measles immunisation (@50%)

$229

3.73

$61

Dominated

       

87

Zinc Fort & CM (@95%) + Measles immunisation (@50%)

$307

4.23

$73

Dominated

       

88

Vit. A Suppl. & Zinc Suppl. (@50%) + Measles immunisation (@50%)

$130

2.61

$50

Dominated

       

89

Vit. A Suppl. & Zinc Suppl. (@80%) + Measles immunisation (@50%)

$215

3.54

$61

Dominated

       

90

Vit. A Suppl. & Zinc Suppl. (@95%) + Measles immunisation (@50%)

$300

4.00

$75

Dominated

       

91

Zinc Suppl. & Zinc Fort (@50%) + Measles immunisation (@50%)

$83

1.20

$69

Dominated

       

92

Zinc Suppl. & Zinc Fort (@80%) + Measles immunisation (@50%)

$113

1.29

$88

Dominated

       

93

Zinc Suppl. & Zinc Fort (@95%) + Measles immunisation (@50%)

$139

1.33

$105

Dominated

       

94

Vit. A Fort., Zinc Fort.& ORT (@50%) + Measles immunisation (@50%)

$287

3.88

$74

Dominated

       

95

Vit. A Fort., Zinc Fort.& ORT (@80%) + Measles immunisation (@50%)

$476

5.57

$85

Dominated

       

96

Vit. A Fort., Zinc Fort.& ORT (@95%) + Measles immunisation (@50%)

$633

6.42

$99

Dominated

       

97

Vit. A Fort., Zinc Fort. & CM (@50%) + Measles immunisation (@50%)

$145

3.28

$44

Dominated

       

98

Vit. A Fort., Zinc Fort. & CM (@80%) + Measles immunisation (@50%)

$229

4.60

$50

Dominated

       

99

Vit. A Fort., Zinc Fort. & CM (@95%) + Measles immunisation (@50%)

$307

5.27

$58

Dominated

       

100

Zinc Fort., ORT & CM (@50%) + Measles immunisation (@50%)

$349

4.94

$71

Dominated

       

101

Zinc Fort., ORT & CM (@80%) + Measles immunisation (@50%)

$595

7.26

$82

Dominated

       

102

Zinc Fort., ORT & CM (@95%) + Measles immunisation (@50%)

$916

8.42

$109

Dominated

       

103

Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@50%)

$363

5.04

$72

Dominated

       

104

Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@50%)

$623

7.42

$84

Dominated

       

105

Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@50%)

$847

8.61

$98

Dominated

       

106

Vit. A Suppl., Zinc Suppl., & CM (@50%) + Measles immunisation (@50%)

$205

4.19

$49

Dominated

       

107

Vit. A Suppl., Zinc Suppl., & CM (@80%) + Measles immunisation (@50%)

$354

6.07

$58

Dominated

       

108

Vit. A Suppl., Zinc Suppl., & CM (@95%) + Measles immunisation (@50%)

$501

7.01

$71

Dominated

       

109

Vit. A Suppl., Zinc Suppl., & ORT (@50%) + Measles immunisation (@50%)

$348

4.79

$73

Dominated

       

110

Vit. A Suppl., Zinc Suppl., & ORT (@80%) + Measles immunisation (@50%)

$602

7.02

$86

Dominated

       

111

Vit. A Suppl., Zinc Suppl., & ORT (@95%) + Measles immunisation (@50%)

$828

8.14

$102

Dominated

       

112

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@50%)

$421

6.48

$65

Dominated

       

113

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@50%)

$740

9.73

$76

Dominated

       

114

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@50%)

$1,135

11.35

$100

Dominated

       

115

Vit. A Fort., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@50%)

$356

5.51

$65

Dominated

       

116

Vit. A Fort., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@50%)

$606

8.18

$74

Dominated

       

117

Vit. A Fort., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@50%)

$821

9.52

$86

Dominated

       

118

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%) + Measles immunisation (@50%)

$145

1.80

$81

Dominated

       

119

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%) + Measles immunisation (@50%)

$235

2.24

$105

Dominated

       

120

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%) + Measles immunisation (@50%)

$323

2.46

$131

Dominated

       

121

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%) + Measles immunisation (@50%)

$1,324

6.54

$202

Dominated

       

122

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%) + Measles immunisation (@50%)

$2,192

9.83

$223

Dominated

       

123

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%) + Measles immunisation (@50%)

$2,765

11.48

$241

Dominated

       

124

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@50%)

$1,259

5.55

$227

Dominated

       

125

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@50%)

$2,058

8.24

$250

Dominated

       

126

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@50%)

$2,667

9.58

$278

Dominated

       

127

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%) + Measles immunisation (@50%)

$220

3.38

$65

Dominated

       

128

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%) + Measles immunisation (@50%)

$375

4.77

$78

Dominated

       

129

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%) + Measles immunisation (@50%)

$524

5.47

$96

Dominated

       

130

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@50%)

$437

5.62

$78

Dominated

       

131

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@50%)

$760

8.36

$91

Dominated

       

132

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@50%)

$1,158

9.73

$119

Dominated

       

133

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@50%)

$1,338

5.66

$237

Dominated

       

134

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@50%)

$2,211

8.42

$263

Dominated

       

135

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@50%)

$2,894

9.79

$295

Dominated

       

136

Vit A. Fort. & Zinc Fort. (@50%) + Measles immunisation (@80%)

$64

2.33

$27

Dominated

       

137

Vit A. Fort. & Zinc Fort. (@80%) + Measles immunisation (@80%)

$69

2.71

$26

Dominated

       

138

Vit A. Fort. & Zinc Fort. (@95%) + Measles immunisation (@80%)

$72

2.90

$25

$29

       

139

Zinc Fort & CM (@50%) + Measles immunisation (@80%)

$158

3.37

$47

Dominated

       

140

Zinc Fort & CM (@80%) + Measles immunisation (@80%)

$243

4.37

$56

Dominated

       

141

Zinc Fort & CM (@95%) + Measles immunisation (@80%)

$321

4.87

$66

Dominated

       

142

Vit. A Suppl. & Zinc Suppl. (@50%) + Measles immunisation (@80%)

$144

3.25

$44

Dominated

       

143

Vit. A Suppl. & Zinc Suppl. (@80%) + Measles immunisation (@80%)

$229

4.18

$55

Dominated

       

144

Vit. A Suppl. & Zinc Suppl. (@95%) + Measles immunisation (@80%)

$314

4.64

$68

Dominated

       

145

Zinc Suppl. & Zinc Fort (@50%) + Measles immunisation (@80%)

$97

1.84

$52

Dominated

       

146

Zinc Suppl. & Zinc Fort (@80%) + Measles immunisation (@80%)

$127

1.93

$66

Dominated

       

147

Zinc Suppl. & Zinc Fort (@95%) + Measles immunisation (@80%)

$153

1.97

$78

Dominated

       

148

Vit. A Fort., Zinc Fort.& ORT (@50%) + Measles immunisation (@80%)

$301

4.52

$67

Dominated

       

149

Vit. A Fort., Zinc Fort.& ORT (@80%) + Measles immunisation (@80%)

$490

6.21

$79

Dominated

       

150

Vit. A Fort., Zinc Fort.& ORT (@95%) + Measles immunisation (@80%)

$647

7.05

$92

Dominated

       

151

Vit. A Fort., Zinc Fort. & CM (@50%) + Measles immunisation (@80%)

$158

3.92

$40

Dominated

       

152

Vit. A Fort., Zinc Fort. & CM (@80%) + Measles immunisation (@80%)

$243

5.24

$46

Dominated

       

153

Vit. A Fort., Zinc Fort. & CM (@95%) + Measles immunisation (@80%)

$321

5.91

$54

Dominated

       

154

Zinc Fort., ORT & CM (@50%) + Measles immunisation (@80%)

$362

5.57

$65

Dominated

       

155

Zinc Fort., ORT & CM (@80%) + Measles immunisation (@80%)

$609

7.90

$77

Dominated

       

156

Zinc Fort., ORT & CM (@95%) + Measles immunisation (@80%)

$930

9.06

$103

Dominated

       

157

Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@80%)

$377

5.67

$66

Dominated

       

158

Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@80%)

$637

8.06

$79

Dominated

       

159

Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@80%)

$861

9.25

$93

Dominated

       

160

Vit. A Suppl., Zinc Suppl., & CM (@50%) + Measles immunisation (@80%)

$219

4.83

$45

Dominated

       

161

Vit. A Suppl., Zinc Suppl., & CM (@80%) + Measles immunisation (@80%)

$368

6.71

$55

Dominated

       

162

Vit. A Suppl., Zinc Suppl., & CM (@95%) + Measles immunisation (@80%)

$515

7.65

$67

Dominated

       

163

Vit. A Suppl., Zinc Suppl., & ORT (@50%) + Measles immunisation (@80%)

$362

5.43

$67

Dominated

       

164

Vit. A Suppl., Zinc Suppl., & ORT (@80%) + Measles immunisation (@80%)

$616

7.66

$80

Dominated

       

165

Vit. A Suppl., Zinc Suppl., & ORT (@95%) + Measles immunisation (@80%)

$842

8.78

$96

Dominated

       

166

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@80%)

$435

7.12

$61

Dominated

       

167

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@80%)

$754

10.36

$73

Dominated

       

168

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@80%)

$1,148

11.99

$96

Dominated

       

169

Vit. A Fort., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@80%)

$370

6.15

$60

Dominated

       

170

Vit. A Fort., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@80%)

$620

8.82

$70

Dominated

       

171

Vit. A Fort., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@80%)

$835

10.16

$82

Dominated

       

172

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%) + Measles immunisation (@80%)

$159

2.44

$65

Dominated

       

173

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%) + Measles immunisation (@80%)

$249

2.88

$86

Dominated

       

174

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%) + Measles immunisation (@80%)

$337

3.10

$109

Dominated

       

175

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%) + Measles immunisation (@80%)

$1,338

7.18

$186

Dominated

       

176

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%) + Measles immunisation (@80%)

$2,206

10.47

$211

Dominated

       

177

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%) + Measles immunisation (@80%)

$2,779

12.11

$229

Dominated

       

178

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@80%)

$1,273

6.19

$206

Dominated

       

179

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@80%)

$2,071

8.88

$233

Dominated

       

180

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@80%)

$2,681

10.22

$262

Dominated

       

181

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%) + Measles immunisation (@80%)

$234

4.02

$58

Dominated

       

182

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%) + Measles immunisation (@80%)

$388

5.41

$72

Dominated

       

183

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%) + Measles immunisation (@80%)

$538

6.11

$88

Dominated

       

184

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@80%)

$450

6.26

$72

Dominated

       

185

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@80%)

$774

9.00

$86

Dominated

       

186

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@80%)

$1,172

10.36

$113

Dominated

       

187

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@80%)

$1,352

6.30

$215

Dominated

       

188

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@80%)

$2,224

9.05

$246

Dominated

       

189

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@80%)

$2,908

10.43

$279

Dominated

       

190

Vit A. Fort. & Zinc Fort. (@50%) + Measles immunisation (@95%)

$83

2.65

$31

Dominated

       

191

Vit A. Fort. & Zinc Fort. (@80%) + Measles immunisation (@95%)

$88

3.03

$29

Dominated

       

192

Vit A. Fort. & Zinc Fort. (@95%) + Measles immunisation (@95%)

$91

3.22

$28

$58

       

193

Zinc Fort & CM (@50%) + Measles immunisation (@95%)

$177

3.69

$48

Dominated

       

194

Zinc Fort & CM (@80%) + Measles immunisation (@95%)

$261

4.69

$56

Dominated

       

195

Zinc Fort & CM (@95%) + Measles immunisation (@95%)

$340

5.19

$65

Dominated

       

196

Vit. A Suppl. & Zinc Suppl. (@50%) + Measles immunisation (@95%)

$163

3.57

$46

Dominated

       

197

Vit. A Suppl. & Zinc Suppl. (@80%) + Measles immunisation (@95%)

$247

4.50

$55

Dominated

       

198

Vit. A Suppl. & Zinc Suppl. (@95%) + Measles immunisation (@95%)

$332

4.96

$67

Dominated

       

199

Zinc Suppl. & Zinc Fort (@50%) + Measles immunisation (@95%)

$115

2.16

$53

Dominated

       

200

Zinc Suppl. & Zinc Fort (@80%) + Measles immunisation (@95%)

$145

2.25

$65

Dominated

       

201

Zinc Suppl. & Zinc Fort (@95%) + Measles immunisation (@95%)

$171

2.29

$75

Dominated

       

202

Vit. A Fort., Zinc Fort.& ORT (@50%) + Measles immunisation (@95%)

$319

4.84

$66

Dominated

       

203

Vit. A Fort., Zinc Fort.& ORT (@80%) + Measles immunisation (@95%)

$508

6.53

$78

Dominated

       

204

Vit. A Fort., Zinc Fort.& ORT (@95%) + Measles immunisation (@95%)

$666

7.37

$90

Dominated

       

205

Vit. A Fort., Zinc Fort. & CM (@50%) + Measles immunisation (@95%)

$177

4.23

$42

Dominated

       

206

Vit. A Fort., Zinc Fort. & CM (@80%) + Measles immunisation (@95%)

$261

5.56

$47

$73

       

207

Vit. A Fort., Zinc Fort. & CM (@95%) + Measles immunisation (@95%)

$340

6.23

$55

Dominated

       

208

Zinc Fort., ORT & CM (@50%) + Measles immunisation (@95%)

$381

5.89

$65

Dominated

       

209

Zinc Fort., ORT & CM (@80%) + Measles immunisation (@95%)

$627

8.22

$76

Dominated

       

210

Zinc Fort., ORT & CM (@95%) + Measles immunisation (@95%)

$949

9.38

$101

Dominated

       

211

Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@95%)

$395

5.99

$66

Dominated

       

212

Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@95%)

$655

8.38

$78

Dominated

       

213

Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@95%)

$879

9.57

$92

Dominated

       

214

Vit. A Suppl., Zinc Suppl., & CM (@50%) + Measles immunisation (@95%)

$237

5.15

$46

Dominated

       

215

Vit. A Suppl., Zinc Suppl., & CM (@80%) + Measles immunisation (@95%)

$386

7.03

$55

$85

       

216

Vit. A Suppl., Zinc Suppl., & CM (@95%) + Measles immunisation (@95%)

$533

7.97

$67

Dominated

       

217

Vit. A Suppl., Zinc Suppl., & ORT (@50%) + Measles immunisation (@95%)

$380

5.75

$66

Dominated

       

218

Vit. A Suppl., Zinc Suppl., & ORT (@80%) + Measles immunisation (@95%)

$634

7.98

$79

Dominated

       

219

Vit. A Suppl., Zinc Suppl., & ORT (@95%) + Measles immunisation (@95%)

$860

9.10

$95

Dominated

       

220

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@95%)

$454

7.44

$61

Dominated

       

221

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@95%)

$772

10.68

$72

$106

       

222

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@95%)

$1,167

12.31

$95

$243

       

223

Vit. A Fort., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@95%)

$389

6.47

$60

Dominated

       

224

Vit. A Fort., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@95%)

$639

9.14

$70

Dominated

       

225

Vit. A Fort., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@95%)

$854

10.48

$81

Dominated

       

226

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%) + Measles immunisation (@95%)

$178

2.76

$64

Dominated

       

227

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%) + Measles immunisation (@95%)

$268

3.20

$84

Dominated

       

228

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%) + Measles immunisation (@95%)

$356

3.42

$104

Dominated

       

229

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%) + Measles immunisation (@95%)

$1,356

7.50

$181

Dominated

       

230

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%) + Measles immunisation (@95%)

$2,224

10.79

$206

Dominated

       

231

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%) + Measles immunisation (@95%)

$2,797

12.43

$225

$12,791

       

232

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@95%)

$1,291

6.51

$198

Dominated

       

233

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@95%)

$2,090

9.20

$227

Dominated

       

234

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@95%)

$2,699

10.54

$256

Dominated

       

235

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%) + Measles immunisation (@95%)

$252

4.34

$58

Dominated

       

236

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%) + Measles immunisation (@95%)

$407

5.73

$71

Dominated

       

237

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%) + Measles immunisation (@95%)

$556

6.43

$87

Dominated

       

238

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@95%)

$469

6.58

$71

Dominated

       

239

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@95%)

$793

9.32

$85

Dominated

       

240

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@95%)

$1,190

10.68

$111

Dominated

       

241

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@95%)

$1,371

6.62

$207

Dominated

       

242

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@95%)

$2,243

9.37

$239

Dominated

       

243

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@95%)

$2,926

10.75

$272

Dominated

       

 

 

 

Table B: [As supplied by authors] Costs, effectiveness and cost-effectiveness ratios of all interventions and combinations for Sear-D in 2000 international dollars

No.

Description of intervention

Yearly Costs (millions Int$)

Yearly DALYs averted (millions)

ACER ($ per DALY averted)

ICER ($ per DALY averted)

               

1

Oral Rehydration Therapy (ORT) (@50%)

$497

2.84

$175

Dominated

   

2

Oral Rehydration Therapy (@80%)

$799

4.55

$176

Dominated

   

3

Oral Rehydration Therapy (@95%)

$998

5.40

$185

Dominated

   

4

Case management for childhood pneumonia (CM) (@50%)

$201

2.65

$76

Dominated

   

5

Case management for childhood pneumonia (@80%)

$323

4.23

$76

Dominated

   

6

Case management for childhood pneumonia (@95%)

$421

5.03

$84

Dominated

   

7

Vitamin A supplementation (@50%)

$50

0.13

$377

Dominated

   

8

Vitamin A supplementation (@80%)

$295

0.21

$1,378

Dominated

   

9

Vitamin A supplementation (@95%)

$429

0.25

$1,686

Dominated

   

10

Vitamin A fortification (@50%)

$18

0.06

$277

Dominated

   

11

Vitamin A fortification (@80%)

$25

0.10

$244

Dominated

   

12

Vitamin A fortification (@95%)

$29

0.12

$237

Dominated

   

13

Provision of supplementary food and nutritional counselling (SF) (@50%)

$4,039

0.31

$13,189

Dominated

   

14

Provision of supplementary food and nutritional counseling ( (@80%)

$6,462

0.49

$13,187

Dominated

   

15

Provision of supplementary food and nutritional counselling (@95%)

$7,684

0.58

$13,206

Dominated

   

16

Provision of supplementary food and nutritional counselling with growth monitoring (SFGM) (@50%)

$2,491

0.31

$8,133

Dominated

   

17

Provision of supplementary food and nutritional counselling with growth monitoring (@80%)

$3,984

0.49

$8,131

Dominated

   

18

Provision of supplementary food and nutritional counselling with growth monitoring(@95%)

$4,742

0.58

$8,150

Dominated

   

19

Zinc supplementation (@50%)

$47

0.94

$50

Dominated

   

20

Zinc supplementation (@80%)

$72

1.51

$48

Dominated

   

21

Zinc supplementation (@95%)

$86

1.79

$48

Dominated

   

22

Zinc fortification (@50%)

$9

0.47

$19

Dominated

   

23

Zinc fortification (@80%)

$11

0.75

$15

Dominated

   

24

Zinc fortification (@95%)

$12

0.90

$14

$14

   

25

ORT & CM (@50%)

$463

5.51

$84

Dominated

   

26

ORT & CM (@80%)

$1,059

8.82

$120

Dominated

   

27

ORT & CM (@95%)

$1,321

10.47

$126

Dominated

   

28

Vit A. Fort. & Zinc Fort. (@50%)

$29

0.75

$39

Dominated

   

29

Vit A. Fort. & Zinc Fort. (@80%)

$42

1.20

$35

Dominated

   

30

Vit A. Fort. & Zinc Fort. (@95%)

$49

1.42

$35

$70

   

31

Zinc Fort & CM (@50%)

$229

3.27

$70

Dominated

   

32

Zinc Fort & CM (@80%)

$365

5.23

$70

Dominated

   

33

Zinc Fort & CM (@95%)

$470

6.21

$76

Dominated

   

34

Vit. A Suppl. & Zinc Suppl. (@50%)

$214

1.67

$128

Dominated

   

35

Vit. A Suppl. & Zinc Suppl. (@80%)

$344

2.68

$129

Dominated

   

36

Vit. A Suppl. & Zinc Suppl. (@95%)

$451

3.18

$142

Dominated

   

37

Zinc Suppl. & Zinc Fort (@50%)

$89

0.80

$111

Dominated

   

38

Zinc Suppl. & Zinc Fort (@80%)

$141

1.28

$110

Dominated

   

39

Zinc Suppl. & Zinc Fort (@95%)

$191

1.52

$126

Dominated

   

40

Vit. A Fort., Zinc Fort.& ORT (@50%)

$525

3.64

$144

Dominated

   

41

Vit. A Fort., Zinc Fort.& ORT (@80%)

$840

5.82

$144

Dominated

   

42

Vit. A Fort., Zinc Fort.& ORT (@95%)

$1,045

6.91

$151

Dominated

   

43

Vit. A Fort., Zinc Fort. & CM (@50%)

$229

3.59

$64

Dominated

   

44

Vit. A Fort., Zinc Fort. & CM (@80%)

$365

5.68

$64

$74

   

45

Vit. A Fort., Zinc Fort. & CM (@95%)

$470

6.75

$70

$99

   

46

Zinc Fort., ORT & CM (@50%)

$667

6.18

$108

Dominated

   

47

Zinc Fort., ORT & CM (@80%)

$1,068

9.89

$108

Dominated

   

48

Zinc Fort., ORT & CM (@95%)

$1,577

11.74

$134

Dominated

   

49

Zinc Suppl., ORT & CM (@50%)

$513

6.71

 

Dominated

   

50

Zinc Suppl., ORT & CM (@80%)

$1,138

10.74

$106

Dominated

   

51

Zinc Suppl., ORT & CM (@95%)

$1,421

12.75

$111

Dominated

   

52

Vit. A Suppl., Zinc Suppl., & CM (@50%)

$384

4.54

$85

Dominated

   

53

Vit. A Suppl., Zinc Suppl., & CM (@80%)

$617

7.26

$85

Dominated

   

54

Vit. A Suppl., Zinc Suppl., & CM (@95%)

$793

8.62

$92

Dominated

   

55

Vit. A Suppl., Zinc Suppl., & ORT (@50%)

$681

4.58

$149

Dominated

   

56

Vit. A Suppl., Zinc Suppl., & ORT (@80%)

$1,093

7.33

$149

Dominated

   

57

Vit. A Suppl., Zinc Suppl., & ORT (@95%)

$1,370

8.70

$157

Dominated

   

58

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%)

$849

7.51

$113

Dominated

   

59

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%)

$1,363

12.02

$113

Dominated

   

60

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%)

$1,955

14.28

$137

Dominated

   

61

Vit. A Fort., Zinc Fort., ORT & CM (@50%)

$687

6.48

$106

Dominated

   

62

Vit. A Fort., Zinc Fort., ORT & CM (@80%)

$1,099

10.37

$106

Dominated

   

63

Vit. A Fort., Zinc Fort., ORT & CM (@95%)

$1,367

12.32

$111

Dominated

   

64

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%)

$243

1.10

$220

Dominated

   

65

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%)

$387

1.77

$219

Dominated

   

66

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%)

$500

2.10

$238

Dominated

   

67

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%)

$3,119

7.57

$412

Dominated

   

68

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%)

$5,310

12.11

$439

Dominated

   

69

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%)

$6,407

14.38

$446

Dominated

   

70

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%)

$3,153

6.52

$484

Dominated

   

71

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%)

$5,044

10.42

$484

Dominated

   

72

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%)

$6,308

12.38

$510

Dominated

   

73

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%)

$413

3.91

$106

Dominated

   

74

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%)

$659

6.26

$105

Dominated

   

75

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%)

$843

7.43

$113

Dominated

   

76

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%)

$878

6.85

$128

Dominated

   

77

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%)

$1,405

10.95

$128

Dominated

   

78

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%)

$2,004

13.01

$154

Dominated

   

79

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%)

$3,343

6.88

$486

Dominated

   

80

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%)

$5,349

11.00

$486

Dominated

   

81

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%)

$6,699

13.07

$513

Dominated

   

82

Vit A. Fort. & Zinc Fort. (@50%) + Measles immunisation (@50%)

$118

1.46

$81

Dominated

   

83

Vit A. Fort. & Zinc Fort. (@80%) + Measles immunisation (@50%)

$131

1.91

$69

Dominated

   

84

Vit A. Fort. & Zinc Fort. (@95%) + Measles immunisation (@50%)

$138

2.14

$64

Dominated

   

85

Zinc Fort & CM (@50%) + Measles immunisation (@50%)

$318

3.98

$80

Dominated

   

86

Zinc Fort & CM (@80%) + Measles immunisation (@50%)

$453

5.94

$76

Dominated

   

87

Zinc Fort & CM (@95%) + Measles immunisation (@50%)

$558

6.92

$81

Dominated

   

88

Vit. A Suppl. & Zinc Suppl. (@50%) + Measles immunisation (@50%)

$302

2.39

$127

Dominated

   

89

Vit. A Suppl. & Zinc Suppl. (@80%) + Measles immunisation (@50%)

$433

3.39

$128

Dominated

   

90

Vit. A Suppl. & Zinc Suppl. (@95%) + Measles immunisation (@50%)

$539

3.89

$139

Dominated

   

91

Zinc Suppl. & Zinc Fort (@50%) + Measles immunisation (@50%)

$177

1.51

$117

Dominated

   

92

Zinc Suppl. & Zinc Fort (@80%) + Measles immunisation (@50%)

$229

1.99

$115

Dominated

   

93

Zinc Suppl. & Zinc Fort (@95%) + Measles immunisation (@50%)

$279

2.23

$125

Dominated

   

94

Vit. A Fort., Zinc Fort.& ORT (@50%) + Measles immunisation (@50%)

$614

4.35

$141

Dominated

   

95

Vit. A Fort., Zinc Fort.& ORT (@80%) + Measles immunisation (@50%)

$928

6.53

$142

Dominated

   

96

Vit. A Fort., Zinc Fort.& ORT (@95%) + Measles immunisation (@50%)

$1,134

7.63

$149

Dominated

   

97

Vit. A Fort., Zinc Fort. & CM (@50%) + Measles immunisation (@50%)

$318

4.30

$74

Dominated

   

98

Vit. A Fort., Zinc Fort. & CM (@80%) + Measles immunisation (@50%)

$453

6.40

$71

Dominated

   

99

Vit. A Fort., Zinc Fort. & CM (@95%) + Measles immunisation (@50%)

$558

7.46

$75

Dominated

   

100

Zinc Fort., ORT & CM (@50%) + Measles immunisation (@50%)

$756

6.89

$110

Dominated

   

101

Zinc Fort., ORT & CM (@80%) + Measles immunisation (@50%)

$1,157

10.60

$109

Dominated

   

102

Zinc Fort., ORT & CM (@95%) + Measles immunisation (@50%)

$1,665

12.45

$134

Dominated

   

103

Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@50%)

$601

7.42

$81

Dominated

   

104

Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@50%)

$1,227

11.45

$107

Dominated

   

105

Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@50%)

$1,509

13.46

$112

Dominated

   

106

Vit. A Suppl., Zinc Suppl., & CM (@50%) + Measles immunisation (@50%)

$472

5.25

$90

Dominated

   

107

Vit. A Suppl., Zinc Suppl., & CM (@80%) + Measles immunisation (@50%)

$705

7.97

$89

Dominated

   

108

Vit. A Suppl., Zinc Suppl., & CM (@95%) + Measles immunisation (@50%)

$882

9.33

$95

Dominated

   

109

Vit. A Suppl., Zinc Suppl., & ORT (@50%) + Measles immunisation (@50%)

$769

5.29

$145

Dominated

   

110

Vit. A Suppl., Zinc Suppl., & ORT (@80%) + Measles immunisation (@50%)

$1,181

8.04

$147

Dominated

   

111

Vit. A Suppl., Zinc Suppl., & ORT (@95%) + Measles immunisation (@50%)

$1,459

9.41

$155

Dominated

   

112

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@50%)

$937

8.23

$114

Dominated

   

113

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@50%)

$1,451

12.74

$114

Dominated

   

114

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@50%)

$2,043

14.99

$136

Dominated

   

115

Vit. A Fort., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@50%)

$776

7.20

$108

Dominated

   

116

Vit. A Fort., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@50%)

$1,187

11.09

$107

Dominated

   

117

Vit. A Fort., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@50%)

$1,456

13.03

$112

Dominated

   

118

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%) + Measles immunisation (@50%)

$331

1.82

$182

Dominated

   

119

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%) + Measles immunisation (@50%)

$475

2.48

$192

Dominated

   

120

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%) + Measles immunisation (@50%)

$589

2.81

$210

Dominated

   

121

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%) + Measles immunisation (@50%)

$3,208

8.28

$387

Dominated

   

122

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%) + Measles immunisation (@50%)

$5,398

12.82

$421

Dominated

   

123

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%) + Measles immunisation (@50%)

$6,496

15.09

$430

Dominated

   

124

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@50%)

$3,241

7.23

$448

Dominated

   

125

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@50%)

$5,132

11.14

$461

Dominated

   

126

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@50%)

$6,396

13.09

$489

Dominated

   

127

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%) + Measles immunisation (@50%)

$501

4.62

$108

Dominated

   

128

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%) + Measles immunisation (@50%)

$748

6.97

$107

Dominated

   

129

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%) + Measles immunisation (@50%)

$931

8.14

$114

Dominated

   

130

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@50%)

$967

7.56

$128

Dominated

   

131

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@50%)

$1,494

11.67

$128

Dominated

   

132

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@50%)

$2,093

13.72

$153

Dominated

   

133

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@50%)

$3,431

7.59

$452

Dominated

   

134

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@50%)

$5,438

11.72

$464

Dominated

   

135

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@50%)

$6,787

13.78

$493

Dominated

   

136

Vit A. Fort. & Zinc Fort. (@50%) + Measles immunisation (@80%)

$147

1.89

$78

Dominated

   

137

Vit A. Fort. & Zinc Fort. (@80%) + Measles immunisation (@80%)

$160

2.34

$68

Dominated

   

138

Vit A. Fort. & Zinc Fort. (@95%) + Measles immunisation (@80%)

$167

2.56

$65

Dominated

   

139

Zinc Fort & CM (@50%) + Measles immunisation (@80%)

$347

4.41

$79

Dominated

   

140

Zinc Fort & CM (@80%) + Measles immunisation (@80%)

$482

6.37

$76

Dominated

   

141

Zinc Fort & CM (@95%) + Measles immunisation (@80%)

$587

7.35

$80

Dominated

   

142

Vit. A Suppl. & Zinc Suppl. (@50%) + Measles immunisation (@80%)

$331

2.81

$118

Dominated

   

143

Vit. A Suppl. & Zinc Suppl. (@80%) + Measles immunisation (@80%)

$462

3.82

$121

Dominated

   

144

Vit. A Suppl. & Zinc Suppl. (@95%) + Measles immunisation (@80%)

$568

4.32

$132

Dominated

   

145

Zinc Suppl. & Zinc Fort (@50%) + Measles immunisation (@80%)

$206

1.94

$106

Dominated

   

146

Zinc Suppl. & Zinc Fort (@80%) + Measles immunisation (@80%)

$258

2.42

$107

Dominated

   

147

Zinc Suppl. & Zinc Fort (@95%) + Measles immunisation (@80%)

$308

2.65

$116

Dominated

   

148

Vit. A Fort., Zinc Fort.& ORT (@50%) + Measles immunisation (@80%)

$643

4.78

$135

Dominated

   

149

Vit. A Fort., Zinc Fort.& ORT (@80%) + Measles immunisation (@80%)

$957

6.96

$137

Dominated

   

150

Vit. A Fort., Zinc Fort.& ORT (@95%) + Measles immunisation (@80%)

$1,162

8.05

$144

Dominated

   

151

Vit. A Fort., Zinc Fort. & CM (@50%) + Measles immunisation (@80%)

$347

4.73

$73

Dominated

   

152

Vit. A Fort., Zinc Fort. & CM (@80%) + Measles immunisation (@80%)

$482

6.82

$71

Dominated

   

153

Vit. A Fort., Zinc Fort. & CM (@95%) + Measles immunisation (@80%)

$587

7.89

$74

Dominated

   

154

Zinc Fort., ORT & CM (@50%) + Measles immunisation (@80%)

$785

7.32

$107

Dominated

   

155

Zinc Fort., ORT & CM (@80%) + Measles immunisation (@80%)

$1,185

11.03

$108

Dominated

   

156

Zinc Fort., ORT & CM (@95%) + Measles immunisation (@80%)

$1,694

12.88

$132

Dominated

   

157

Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@80%)

$630

7.85

$80

Dominated

   

158

Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@80%)

$1,256

11.88

$106

Dominated

   

159

Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@80%)

$1,538

13.89

$111

Dominated

   

160

Vit. A Suppl., Zinc Suppl., & CM (@50%) + Measles immunisation (@80%)

$501

5.67

$88

Dominated

   

161

Vit. A Suppl., Zinc Suppl., & CM (@80%) + Measles immunisation (@80%)

$734

8.40

$87

Dominated

   

162

Vit. A Suppl., Zinc Suppl., & CM (@95%) + Measles immunisation (@80%)

$911

9.76

$93

Dominated

   

163

Vit. A Suppl., Zinc Suppl., & ORT (@50%) + Measles immunisation (@80%)

$798

5.72

$139

Dominated

   

164

Vit. A Suppl., Zinc Suppl., & ORT (@80%) + Measles immunisation (@80%)

$1,210

8.47

$143

Dominated

   

165

Vit. A Suppl., Zinc Suppl., & ORT (@95%) + Measles immunisation (@80%)

$1,488

9.84

$151

Dominated

   

166

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@80%)

$966

8.65

$112

Dominated

   

167

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@80%)

$1,480

13.16

$112

Dominated

   

168

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@80%)

$2,072

15.42

$134

Dominated

   

169

Vit. A Fort., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@80%)

$805

7.62

$106

Dominated

   

170

Vit. A Fort., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@80%)

$1,216

11.51

$106

Dominated

   

171

Vit. A Fort., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@80%)

$1,484

13.46

$110

Dominated

   

172

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%) + Measles immunisation (@80%)

$360

2.24

$161

Dominated

   

173

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%) + Measles immunisation (@80%)

$504

2.91

$173

Dominated

   

174

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%) + Measles immunisation (@80%)

$618

3.24

$191

Dominated

   

175

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%) + Measles immunisation (@80%)

$3,237

8.71

$372

Dominated

   

176

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%) + Measles immunisation (@80%)

$5,427

13.25

$410

Dominated

   

177

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%) + Measles immunisation (@80%)

$6,524

15.52

$420

Dominated

   

178

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@80%)

$3,270

7.65

$427

Dominated

   

179

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@80%)

$5,161

11.56

$446

Dominated

   

180

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@80%)

$6,425

13.52

$475

Dominated

   

181

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%) + Measles immunisation (@80%)

$530

5.05

$105

Dominated

   

182

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%) + Measles immunisation (@80%)

$777

7.40

$105

Dominated

   

183

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%) + Measles immunisation (@80%)

$960

8.57

$112

Dominated

   

184

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@80%)

$995

7.99

$125

Dominated

   

185

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@80%)

$1,523

12.09

$126

Dominated

   

186

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@80%)

$2,122

14.15

$150

Dominated

   

187

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@80%)

$3,460

8.02

$432

Dominated

   

188

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@80%)

$5,467

12.14

$450

Dominated

   

189

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@80%)

$6,816

14.21

$480

Dominated

   

190

Vit A. Fort. & Zinc Fort. (@50%) + Measles immunisation (@95%)

$168

2.10

$80

Dominated

   

191

Vit A. Fort. & Zinc Fort. (@80%) + Measles immunisation (@95%)

$181

2.55

$71

Dominated

   

192

Vit A. Fort. & Zinc Fort. (@95%) + Measles immunisation (@95%)

$188

2.78

$68

Dominated

   

193

Zinc Fort & CM (@50%) + Measles immunisation (@95%)

$368

4.62

$80

Dominated

   

194

Zinc Fort & CM (@80%) + Measles immunisation (@95%)

$504

6.58

$77

Dominated

   

195

Zinc Fort & CM (@95%) + Measles immunisation (@95%)

$609

7.56

$80

Dominated

   

196

Vit. A Suppl. & Zinc Suppl. (@50%) + Measles immunisation (@95%)

$352

3.03

$116

Dominated

   

197

Vit. A Suppl. & Zinc Suppl. (@80%) + Measles immunisation (@95%)

$483

4.03

$120

Dominated

   

198

Vit. A Suppl. & Zinc Suppl. (@95%) + Measles immunisation (@95%)

$590

4.53

$130

Dominated

   

199

Zinc Suppl. & Zinc Fort (@50%) + Measles immunisation (@95%)

$227

2.15

$106

Dominated

   

200

Zinc Suppl. & Zinc Fort (@80%) + Measles immunisation (@95%)

$279

2.63

$106

Dominated

   

201

Zinc Suppl. & Zinc Fort (@95%) + Measles immunisation (@95%)

$330

2.87

$115

Dominated

   

202

Vit. A Fort., Zinc Fort.& ORT (@50%) + Measles immunisation (@95%)

$664

4.99

$133

Dominated

   

203

Vit. A Fort., Zinc Fort.& ORT (@80%) + Measles immunisation (@95%)

$978

7.17

$136

Dominated

   

204

Vit. A Fort., Zinc Fort.& ORT (@95%) + Measles immunisation (@95%)

$1,184

8.27

$143

Dominated

   

205

Vit. A Fort., Zinc Fort. & CM (@50%) + Measles immunisation (@95%)

$368

4.94

$74

Dominated

   

206

Vit. A Fort., Zinc Fort. & CM (@80%) + Measles immunisation (@95%)

$504

7.04

$72

Dominated

   

207

Vit. A Fort., Zinc Fort. & CM (@95%) + Measles immunisation (@95%)

$609

8.10

$75

$102

   

208

Zinc Fort., ORT & CM (@50%) + Measles immunisation (@95%)

$806

7.53

$107

Dominated

   

209

Zinc Fort., ORT & CM (@80%) + Measles immunisation (@95%)

$1,207

11.24

$107

Dominated

   

210

Zinc Fort., ORT & CM (@95%) + Measles immunisation (@95%)

$1,715

13.09

$131

Dominated

   

211

Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@95%)

$651

8.07

$81

Dominated

   

212

Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@95%)

$1,277

12.09

$106

Dominated

   

213

Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@95%)

$1,560

14.11

$111

$158

   

214

Vit. A Suppl., Zinc Suppl., & CM (@50%) + Measles immunisation (@95%)

$522

5.89

$89

Dominated

   

215

Vit. A Suppl., Zinc Suppl., & CM (@80%) + Measles immunisation (@95%)

$756

8.61

$88

Dominated

   

216

Vit. A Suppl., Zinc Suppl., & CM (@95%) + Measles immunisation (@95%)

$932

9.97

$93

Dominated

   

217

Vit. A Suppl., Zinc Suppl., & ORT (@50%) + Measles immunisation (@95%)

$819

5.93

$138

Dominated

   

218

Vit. A Suppl., Zinc Suppl., & ORT (@80%) + Measles immunisation (@95%)

$1,232

8.68

$142

Dominated

   

219

Vit. A Suppl., Zinc Suppl., & ORT (@95%) + Measles immunisation (@95%)

$1,509

10.06

$150

Dominated

   

220

Vit. A Suppl., Zinc Suppl., ORT & CM (@50%) + Measles immunisation (@95%)

$987

8.87

$111

Dominated

   

221

Vit. A Suppl., Zinc Suppl., ORT & CM (@80%) + Measles immunisation (@95%)

$1,501

13.38

$112

Dominated

   

222

Vit. A Suppl., Zinc Suppl., ORT & CM (@95%) + Measles immunisation (@95%)

$2,094

15.63

$134

$350

   

223

Vit. A Fort., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@95%)

$826

7.84

$105

Dominated

   

224

Vit. A Fort., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@95%)

$1,237

11.73

$106

Dominated

   

225

Vit. A Fort., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@95%)

$1,506

13.67

$110

Dominated

   

226

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@50%) + Measles immunisation (@95%)

$382

2.46

$155

Dominated

   

227

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@80%) + Measles immunisation (@95%)

$525

3.12

$168

Dominated

   

228

Vit. A Suppl., Vit. A Fort., Zinc Suppl., & Zinc Fort. (@95%) + Measles immunisation (@95%)

$639

3.45

$185

Dominated

   

229

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@50%) + Measles immunisation (@95%)

$3,258

8.92

$365

Dominated

   

230

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@80%) + Measles immunisation (@95%)

$5,449

13.46

$405

Dominated

   

231

Vit. A Suppl., Zinc Suppl., SFGM, ORT & CM (@95%) + Measles immunisation (@95%)

$6,546

15.73

$416

$44,384

   

232

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@95%)

$3,291

7.87

$418

Dominated

   

233

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@95%)

$5,182

11.78

$440

Dominated

   

234

Vit. A Fort, Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@95%)

$6,447

13.73

$469

Dominated

   

235

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@50%) + Measles immunisation (@95%)

$552

5.26

$105

Dominated

   

236

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@80%) + Measles immunisation (@95%)

$798

7.61

$105

Dominated

   

237

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort. & CM (@95%) + Measles immunisation (@95%)

$981

8.78

$112

Dominated

   

238

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@50%) + Measles immunisation (@95%)

$1,017

8.20

$124

Dominated

   

239

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@80%) + Measles immunisation (@95%)

$1,544

12.31

$125

Dominated

   

240

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., ORT & CM (@95%) + Measles immunisation (@95%)

$2,143

14.36

$149

Dominated

   

241

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@50%) + Measles immunisation (@95%)

$3,482

8.23

$423

Dominated

   

242

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@80%) + Measles immunisation (@95%)

$5,488

12.36

$444

Dominated

   

243

Vit. A Suppl., Vit. A Fort., Zinc Suppl., Zinc Fort., SFGM, ORT & CM (@95%) + Measles immunisation (@95%)

$6,837

14.42

$474

Dominated

   

 

 

Annex A: [As supplied by authors]

Case management for childhood pneumonia and oral rehydration therapy: These are the original algorithmic approaches developed by WHO wherein specific actions, e.g. provision of antibiotics for pneumonia (or oral rehydration solution for diarrhea) and /or hospitalization are triggered by the detection of specific signs and symptoms.

Provision of supplementary food during weaning with counselling on nutrition: One-time intensive counselling is provided to mothers on the appropriate complementary feeding practices and on the importance of continued breast-feeding. In addition, all infants, aged six months to one year, regardless of nutritional status, are provided with ready-to-mix supplementary food, which is collected every two months from a health centre by the caregiver. It was then assumed that each cohort of children exposed to this intervention would continue to reap the benefits subsequently because of the knowledge and attitudes retained by the caregiver.

Provision of supplementary food with nutrition counselling and growth monitoring and promotion (targeted): All caregivers are given an initial intensive counselling session on appropriate complementary feeding practices and the importance of continued breastfeeding. Caregivers are provided with growth charts and during quarterly visits, the weight of the child is plotted and any deviations from expected weight gain discussed. Solutions are suggested and targets for weight gain are set. In addition, ready-to-mix supplementary food is provided to all children from age six months to one year who are mild to severely underweight.

Vitamin A supplementation: Oral Vitamin A supplements are provided to all children under five years of age twice a year at a health centre. The dose is 200,000 i.u. for children from their first birthday. For those less than one year of age, the dose is 50-100,000 i.u. Effectiveness of the intervention is adjusted by an assumed adherence of 75%.

Vitamin A fortification: Fortification of a food staple with Vitamin A (in this case assumed to be sugar), whether locally produced or imported, or whether for industrial or domestic use, is assured through legislation. The amount of Vitamin A required is calculated based on a consideration of the expected sources of Vitamin A and the average per capita intake of sugar in different settings. Intervention includes provision of guidelines for quality control of sugar fortification in the mills, regular visits to mills by inspectors, and regular sampling and testing of sugar taken from mills, markets and homes for Vitamin A content. Samples from homes are taken opportunistically during mass surveys carried out for other purposes. Effectiveness is adjusted using assumptions regarding access to processed food.

Zinc supplementation: During one of the first immunisations contacts in infancy, the health worker prescribes zinc gluconate or sulfate, 10 mg in solution as part of a routine. Thereafter, the zinc solution is administered by a caregiver at home daily to every child until the child reaches five years of age. Effectiveness of the intervention is adjusted by an assumed adherence of 60% for medications being taken daily.

Zinc fortification: The intervention has the same characteristics as for Vitamin A fortification except the nutrient added is zinc oxide and the food vehicle is wheat, not sugar. Note that in the absence of documented field experience, the effectiveness of zinc fortification was modelled relative to the effectiveness of supplementation at approximately the level of vitamin a supplementation to fortification.

Measles Immunization: Single dose measles vaccine injected at the age of nine

months to a child by a professional in a health facility.





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