Table A Key baseline patient characteristics by diagnosis (n=28,825) [posted as supplied by author]

Characteristic	STEMI	NSTEMI	Unstable angina	P value
N	9833	9007	9985	�
Median age (years) (IQR)	64 (54, 74)	68 (57, 77)	66 (56, 75)	<0.001
Men (%)	6919 (71)	5939 (66)	6262 (63)	<0.001
Killip class (%)
I	7715 (80)	6833 (78)	8335 (86)	<0.001 (4 � 3 comparison)
II	1334 (14)	1349 (15)	1057 (11)
III	386 (4.0)	543 (6.2)	213 (2.2)
IV	193 (2.0)	73 (0.8)	62 (0.6)
Medical history (%)	�	�	�	�
Stroke	642 (6.6)	899 (10)	831 (8.4)	<0.001
PCI	727 (7.4)	1228 (14)	2420 (24)	<0.001
CABG	487 (5.0)	1183 (13)	1854 (19)	<0.001
Angiogram for CAD	1271 (13)	2467 (28)	4019 (43)	<0.001
Positive stress test	389 (4.0)	864 (9.8)	1704 (17)	<0.001
Myocardial infarction	1860 (19)	2836 (32)	4039 (41)	<0.001
Hypertension	5004 (57)	5491 (61)	6495 (66)	<0.001
Diabetes mellitus	2077 (21)	2424 (27)	2545 (26)	<0.001

CABG, coronary artery bypass grafting; CAD, coronary artery disease; IQR, interquartile range; NSTEMI, non-ST-segment elevation myocardial infarction; PCI, percutaneous coronary intervention; STEMI, ST-segment elevation myocardial infarction

�

Table B Geographical trends in the use of invasive procedures in hospitals with and without access to a catheterization laboratory [posted as supplied by author]

�	Catheterization laboratory N=22,096	No catheterization laboratory N=6729	P value
PCI	�	�	�
Overall (%)	8941 (41)	253 (3.9)	<0.001
USA (%)	2199 (40)	123 (10)	<0.001
Europe (%)	4523 (48)	60 (2.0)	<0.001
Australia/New Zealand/Canada (%)	746 (28)	18 (1.3)	<0.001
Argentina/Brazil (%)	1473 (32)	52 (5.7)	<0.001
CABG	�	�	�
Overall (%)	1554 (7.1)	46 (0.7)	<0.001
USA (%)	589 (11)	19 (1.6)	<0.001
Europe (%)	340 (3.7)	6 (0.2)	<0.001
Australia/New Zealand/Canada (%)	169 (6.5)	12 (0.9)	<0.001
Argentina/Brazil (%)	456 (10)	9 (1.0)	<0.001

PCI, percutaneous coronary intervention; CABG, coronary artery bypass grafting

�

Table C Use of percutaneous coronary intervention and coronary artery bypass grafting according to diagnosis and access to a catheterization laboratory [posted as supplied by author]

�	STEMI		NSTEMI		Unstable angina
�	Cath+	Cath-	Cath+	Cath-	Cath+	Cath-
N	7847	1986	6991	2016	7258	2727
PCI (%)	4238 (54)	83 (4.3)*	2667 (38)	88 (4.6)*	2036 (28)	82 (3.1)*
CABG (%)	371 (4.8)	7 (0.4)*	690 (9.9)	17 (0.9)*	493 (6.9)	22 (0.8)*

CABG, coronary artery bypass grafting; cath+, hospitals with access to catheterization facilities; cath-, hospitals without access to catheterization facilities; NSTEMI, non-ST-segment elevation myocardial infarction; PCI, percutaneous coronary intervention; STEMI, ST-segment elevation myocardial infarction

*P<0.001