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Participating hospitals: Almere, Flevo Hospital; Alphen a/d Rijn, Rijnland Hospital; Amersfoort, Meander Medical Center; Amsterdam, BovenIJ Hospital; Apeldoorn, Gelre Hospital; Baarn, Meander Medical Center; Blaricum, Hospital Gooi-Noord; Gouda, Groene Hart Hospital; Alexander and Carolus, ‘s Hertogenbosch, Jeroen Bosch Hospital; Leiden, University Medical Center Leiden; Leiderdorp, Rijnland Hospital; Lelystad, IJsselmeer Hospital; Nieuwegein, Stichting Sint Antonius Hospital; Rotterdam, Sophia Children’s Hospital; Schiedam, Vlietland Hospital; Utrecht, Mesos Medical Center, location Oudenrijn and Overvecht; Utrecht, Wilhelmina Children’s Hospital; Vlaardingen, Vlietland Hospital; Voorburg, Reinier de Graaf Hospital; Woerden, Hofpoort Hospital; Zwolle, Isala Clinics, location Weezenlanden and Sophia. Executive steering committee: AAA Bak, MD PhD; PPG van Benthem, MD PhD; E Buskens, MD PhD; A Fleer, MD PhD; DE Grobbee, MD PhD ; JLL Kimpen, MD PhD; EAM Sanders, MD PhD; ThJM Verheij, MD PhD.